Results 11 to 20 of about 74,056 (238)

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

Estimating the risk of aflatoxin-induced liver cancer in Tanzania based on biomarker data.

PLoS ONE, 2021
Evidence about the magnitude of the aflatoxin menace can help policy makers appreciate the importance of the problem and strengthen policies to support aflatoxin mitigation measures. In this study, we estimated aflatoxin-induced liver cancer risk in 2016
Martin E Kimanya, Michael N Routledge, Emmanuel Mpolya, Chibundu N Ezekiel, Candida P Shirima, Yun Yun Gong   +5 more
doaj   +1 more source

Complex regulation of the aflatoxin biosynthesis gene cluster of Aspergillus flavus in relation to various combinations of water activity and temperature [PDF]

, 2009
A microarray analysis was performed to study the effect of varying combinations of water activity and temperature on the activation of aflatoxin biosynthesis genes in Aspergillus flavus grown on YES medium. Generally A.
Abdel-Hadi, Ahmed, Geisen, Rolf, Magan, Naresh, Schmidt-Heydt, Markus   +3 more
core   +1 more source

Determination of aflatoxin level in peanut using immunoaffinity column combined with ELISA

Environment Conservation Journal, 2011
Peanut (Arachis hypogaea L.) is a largest source of edible oil in India, extensively consumed in the central and western parts of the country.  The variability in the total aflatoxin and aflatoxin B1 levels in the different peanut samples collected was ...
Harish Chandra, Anil Bhatia, O. P. Sidhu, A. R. Nautiyal, H. M. Behl   +4 more
doaj   +1 more source

Ameliorative effect of nanocurcumin and Saccharomyces cell wall alone and in combination against aflatoxicosis in broilers

BMC Veterinary Research, 2022
Background The adverse effect of aflatoxin in broilers is well known. However, dietary supplementation of Saccharomyces cell wall and/or Nanocurcumin may decrease the negative effect of aflatoxin B1 because of the bio-adsorbing feature of the functional ...
Aya Ashry, Nabil M. Taha, Mohamed A. Lebda, Walied Abdo, Eman M. El-Diasty, Sabreen E. Fadl, Mohamed Morsi Elkamshishi   +6 more
doaj   +1 more source

Assessment of the Effect of Satureja montana and Origanum virens Essential Oils on Aspergillus flavus Growth and Aflatoxin Production at Different Water Activities [PDF]

, 2020
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Aflatoxin ...
Garcia-Cela, Esther, Garcia-Diaz, Marta, Gil-Serna, Jessica, Magan, Naresh, Medina, Angel, Patino, Belen   +5 more
core   +5 more sources

Dietary aflatoxin exposure of lactating mothers of children 0–6 months in Makueni County, Kenya

Maternal and Child Nutrition, 2023
The southeastern region of Kenya is prone to aflatoxin outbreaks, yet maternal and infant aflatoxin intake levels remain unclear. We determined dietary aflatoxin exposure of 170 lactating mothers breastfeeding children aged 6 months and below in a ...
Isaac O. Ogallo, Dasel W. M. Kaindi, George O. Abong, Alice M. Mwangi   +3 more
doaj   +1 more source

Negligible effects of tryptophan on the aflatoxin adsorption of sodium bentonite [PDF]

, 2014
The main objective of this study was to determine if the competitive adsorption of tryptophan (Trp) and aflatoxin B1 (AFB1) could potentially affect the ability of a sodium bentonite (NaB) to prevent aflatoxicosis in monogastric animals.
Chiacchiera, Stella Maris, Copia, P., Dalcero, Ana Maria, Magnoli, Alejandra Paola, Magnoli, Carina Elizabeth, Monge, Maria del Pilar   +5 more
core   +1 more source

Mycotoxin exposure assessments in a multi-center European validation study by 24-hour dietary recall and biological fluid sampling [PDF]

, 2020
The European Food Consumption Validation (EFCOVAL) project includes 600 men and women from Belgium, the Czech Republic, France, the Netherlands, and Norway, who had given serum and 24-hour urine samples, and completed 24-hour dietary recall (24-HDR ...
Abbeddou, Souheila, Arcella, Davide, Claeys, Liesel, De Boevre, Marthe, De Keyzer, Willem, De Ruyck, Karl, De Saeger, Sarah, De Vries, Jeanne, Huybrechts, Inge, Ocke, Marga, Ruprich, Jiri, Yang, Shupeng   +11 more
core   +1 more source

Chronic Aflatoxin Exposure and Cognitive and Language Development in Young Children of Bangladesh: A Longitudinal Study

Toxins, 2022
Aflatoxin can cross the blood–brain barrier, damage brain tissues, and have the potential to harm the development of the human brain. Although dietary aflatoxin exposure is common in children, there is a paucity of data on aflatoxin exposure and child ...
Mustafa Mahfuz, Md. Shabab Hossain, Md. Ashraful Alam, Md. Amran Gazi, Shah Mohammad Fahim, Baitun Nahar, Tahmeed Ahmed   +6 more
doaj   +1 more source