The effect of early life aflatoxin exposure on growth, immune function and cancer predisposition [PDF]
, 2013 Aflatoxin exposure through contamination of dietary staples is prevalent in developing regions such as sub-Saharan Africa. Aflatoxin exposure has been linked to a G→T transversion in p53, which has been suggested to be the main mechanism of aflatoxin ...
Castelino, Jovita Marie
core +6 more sources
Molecular ecology of aspergillus section flavi species : approaches to understand the role of aflatoxin genes in aflatoxin biosynthesis [PDF]
, 2011 This is the first study to integrate and correlate the effect of ecophysiological factors on the life cycle of Aspergillus flavus by carrying out complementary work on gene expression of the aflatoxin gene cluster, with growth, sporulation and ...
Abdel-Hadi, Ahmed
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Impact of ecophysiological factors on biocontrol of aflatoxin contamination of maize by atoxigenic aspergillus flavus strains [PDF]
, 2013 This study has (a) evaluated the biodiversity in toxigenic mycobiota associated with maize from subsistence farmers’ stores in five climatic regions of Lesotho in two seasons, (b) compared the effect of ecophysiological factors on interactions between ...
Mohale, Sejakhosi Alexis
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TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
Biodiversity of mycotoxigenic aspergillus species in Egyptian peanuts and strategies for minimizing aflatoxin contamination [PDF]
, 2010 Peanuts are an important crop grown in Egypt for either local consumption or export to European markets. The present study examined the importance of mycotoxigenic Aspergilli in Egyptian peanuts from five different regions (Alexandria, El-Beheira, El-
Sultan, Yousef Yasseen Abdel-Rahmin
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Estimating the risk of aflatoxin-induced liver cancer in Tanzania based on biomarker data.
PLoS ONE, 2021 Evidence about the magnitude of the aflatoxin menace can help policy makers appreciate the importance of the problem and strengthen policies to support aflatoxin mitigation measures. In this study, we estimated aflatoxin-induced liver cancer risk in 2016
Martin E Kimanya +5 more
doaj +1 more source
Crop Journal, 2018 Simple sequence repeats (SSRs) are important molecular markers for assessing genetic diversity in Arachis hypogaea L. and many other crops and constructing genetic linkage maps for important agricultural traits.
Houmiao Wang +9 more
doaj +1 more source
Determination of aflatoxin level in peanut using immunoaffinity column combined with ELISA
Environment Conservation Journal, 2011 Peanut (Arachis hypogaea L.) is a largest source of edible oil in India, extensively consumed in the central and western parts of the country. The variability in the total aflatoxin and aflatoxin B1 levels in the different peanut samples collected was ...
Harish Chandra +4 more
doaj +1 more source
BMC Veterinary Research, 2022 Background The adverse effect of aflatoxin in broilers is well known. However, dietary supplementation of Saccharomyces cell wall and/or Nanocurcumin may decrease the negative effect of aflatoxin B1 because of the bio-adsorbing feature of the functional ...
Aya Ashry +6 more
doaj +1 more source
Postweaning exposure to aflatoxin results in impaired child growth: A longitudinal study in Benin, west Africa [PDF]
, 2004 Aflatoxins are dietary contaminants that are hepatocarcinogenic and immunotoxic and cause growth retardation in animals, but there is little evidence concerning the latter two parameters in exposed human populations.
Turner, Paul C +36 more
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