Results 21 to 30 of about 28,295 (197)

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

open access: yesHepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam   +10 more
wiley   +1 more source

Characterization of a Fungal Modular Polyketide Synthase System Reveals an Unusual Strategy for Polyketide Chain Initiation

open access: yesAngewandte Chemie, EarlyView.
Fungal modular polyketide synthases (PKSs) remain largely unexplored. Functional characterization of the LasC/LasD assembly line established its role in strasseriolide C biosynthesis and suggested an unexpected strategy for chain initiation, in which a malonyl unit is transferred from the module 2 acyl carrier protein (ACP) domains to the loading ACP ...
Qiaolin Ji   +5 more
wiley   +2 more sources

Effect of Hydroethanolic Saffron petals’ extract on performance, carcass characteristics and blood parameters of Japanese quails challenged by aflatoxin [PDF]

open access: yesZirā̒at va Fanāvarī-i Za̒farān, 2018
The purpose of this study is to investigate the effect of Hydroethanolic saffron petals’ extract (HSPE) on the performance, carcass characteristics and blood biochemical parameters of Japanese quails challenged with Aflatoxin B1.
Seyyed Javad Hosseini-Vashan   +2 more
doaj   +1 more source

Chronic Aflatoxin Exposure and Cognitive and Language Development in Young Children of Bangladesh: A Longitudinal Study

open access: yesToxins, 2022
Aflatoxin can cross the blood–brain barrier, damage brain tissues, and have the potential to harm the development of the human brain. Although dietary aflatoxin exposure is common in children, there is a paucity of data on aflatoxin exposure and child ...
Mustafa Mahfuz   +6 more
doaj   +1 more source

Aflatoxin Contamination in Wheat Flour Samples from Golestan Province, Northeast of Iran [PDF]

open access: yesIranian Journal of Public Health, 2012
Background: Due to the high toxicity of aflatoxin and its effects on public health, determination of aflatoxin level in Wheat flour samples in the Golestan province, north of Iran was investigated.
F Ghasemi Kebria   +7 more
doaj   +2 more sources

ANALYSIS OF AFLATOXIN B1, B2, G1, G2 LEVELS IN FRIED ONIONS PRODUCED IN PALU USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) METHOD

open access: yesJurnal Pangan dan Agroindustri
Aflatoxin, produced by Aspergillus flavus and Aspergillus paraciticus, commonly contaminates agricultural and processed products. This study aims to analyze aflatoxin levels in fried onions produced in Palu through high-performance liquid chromatography (
Putu Ayu Warmadewi, Qabul Dinanta Utama
doaj   +1 more source

Fungal Biodeterioration, Aflatoxin Contamination, and Nutrient Value of “Suya Spices”

open access: yesScientifica, 2016
This work aimed to analyze the nutrient values, examine the biodeteriorating fungi biota, and analyze the mycotoxin contents of “Suya spices.” Fungi with highest percentage occurrence on all the samples are Aspergillus niger, Aspergillus flavus ...
Segun Gbolagade Jonathan   +2 more
doaj   +1 more source

A mini review on aflatoxin exposure in Malaysia: past, present and future

open access: yesFrontiers in Microbiology, 2013
This mini review article described the exposure of aflatoxin in Malaysia, including its presence in the foodstuffs and the detection of aflatoxin biomarkers in human biological samples.
Mohd Redzwan eSabran   +3 more
doaj   +1 more source

Mycological aspects of ostrich meat products with special reference to toxigenic moulds [PDF]

open access: yesVeterinary Medical Journal - Giza, 2010
Ostrich luncheon meat and frankfurter samples were produced locally in Egypt, and relatively highly contaminated by both moulds and yeasts and aflatoxin residues.
Shabana E, Sultan Hanaa
doaj   +1 more source

Compound Abrus cantoniensis Extract Alleviates AFB1‐Induced Liver Injury by Regulating PI3K‐AKT Pathway and Gut Microbiota/Butyrate Metabolism

open access: yesAdvanced Science, EarlyView.
ACCE has a good alleviating effect on AFB1‐induced liver injury, and this alleviating effect is related to the PI3K‐AKT pathway regulated by ACCE and the butyrate metabolism of gut microbiota. ABSTRACT Aflatoxin B1 (AFB1) is a potent hepatotoxin commonly ingested through contaminated food. Abrus cantoniensis Hance, a traditional Chinese medicinal herb,
Hongjie Hu   +12 more
wiley   +1 more source

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