Results 51 to 60 of about 137,543 (205)

The Bile Acid Signaling Axis: Deciphering the Roles of FXR and TGR5 in Hepatic Steatosis, Fibrosis, and Cancer

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Bile acids (BAs) serve not only as emulsifiers for lipid digestion but also as essential signaling molecules, governing various physiological and pathological processes through their interaction with the farnesoid X receptor (FXR) and the takeda G protein‐coupled receptor 5 (TGR5).
Jie Liu, Kui Sun, Hongmei Liu, Meiyang Zhu, Chunmeng Li, Yuqi He, Lin Qin   +6 more
wiley   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, Volume 13, Issue 54, 28 September 2026.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

A seasonal study for determination of aflatoxin M1 level in dairy products in Iranshahr, Iran

Current Medical Mycology, 2016
Background and Purpose :Aflatoxin M1, in milk and dairy products, is classified by the International Agency for Research on Cancer as human carcinogens (class 2B).
Nooshin Sohrabi, Hany Gharahkoli
doaj  

The use of the two different mycotoxin deactivators in the nutrition of dairy cows

Mljekarstvo, 2022
The aim of this study was to investigate the effect of two different commercial products for mycotoxin deactivation in the dairy cows’ nutrition. The research was done on the 18 dairy cows in the different phase of lactation, with the average production ...
Igor Jajić, Saša Krstović, Miroslava Polovinski-Horvatović, Ivan Vojnić Purčar   +3 more
doaj  

Presence of Aflatoxin M1 in Commercial Milk in Paraguay

Journal of Food Protection, 2021
The presence of aflatoxin M1 (AFM1) in milk is a public health concern because milk is a significant part of human diets worldwide. In economies where AFM1 monitoring is low or nonexistent, the possibility of AFM1 contamination might be increased. Our study was conducted to detect and quantify AFM1 in fluid milk and milk drinks of various brands, fat ...
Andrea Alejandra Arrúa, Pablo David Arrúa, Juliana Moura-Mendes, Cinthia Cazal, Francisco Paulo Ferreira, Cristhian Javier Grabowski, Horacio Daniel Lopez-Nicora, Danilo Fernández Rios   +7 more
openaire   +2 more sources

Groundnut Improvement for Aflatoxin Resistance: Progress and Opportunities

Food and Energy Security, Volume 15, Issue 5, September/October 2026.
ABSTRACT Groundnut, or peanut, is an industrial oilseed crop that serves the food and feed industries and provides income along the value chain. Pre‐ and post‐harvest aflatoxin contamination, caused by Aspergillus spp., hinders the food and feed value and market opportunities of groundnut products. Developing and deploying aflatoxin‐resistant varieties
Tullu Tadessa Asefa, Hussein Shimelis, Janila Pasupuleti, Seltene Abady Tesfamariam   +3 more
wiley   +1 more source

AFLATOXIN EXCRETION THROUGH MILK

Archives of Veterinary Medicine, 2008
In the period January to June 2006 the samples of feed were collected from feed factories in Southern Baåka and Srem district. The samples of raw milk and full mix were taken from 5 dairy farms. A total of 50 raw milk samples was examined.
Milica Živkov Baloš, Željko Mihaljev, Mira Kovačević, Dejan Bugarski   +3 more
doaj   +1 more source

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 313-323, August 2026.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory, Gonzalo Villapalos Garcia, Dora Koller, Solomon Adams, Chad A. Bousman, Evangelia Eirini Tsermpini, Michelle Whirl‐Carrillo, Amy J. Turner, Volker M. Lauschke, Mohamed Nagy, Erin C. Boone, Teri E. Klein, Pablo Zubiaur, Andrea Gaedigk   +13 more
wiley   +1 more source

Doses of Immunogen Contribute to Specificity Spectrums of Antibodies against Aflatoxin

Toxins, 2017
Research about antibody specificity spectra was conducted to develop single-specific antibodies or broad-specific antibodies. Aflatoxins, as one class of high-toxicity mycotoxins, were selected as the research targets to investigate the effect of the ...
Peiwu Li, Jing Wu, Li Zhang, Zhiyong Fan, Tingting Yu, Feng Jiang, Xiaoqian Tang, Zhaowei Zhang, Wen Zhang, Qi Zhang   +9 more
doaj   +1 more source

Production of a monoclonal antibody against aflatoxin M1 and its application for detection of aflatoxin M1 in fortified milk

Journal of Food and Drug Analysis, 2016
Aflatoxin M1 (AFM1) is a toxic metabolite of the fungal product aflatoxin found in milk. For food safety concern, maximum residual limits of AFM1 in milk and dairy products have been differently enforced in many countries. A suitable detection method is required to screen a large number of product samples for the AFM1 contamination.
Chadseesuwan, Umarphorn, Sangdokmai, Apinya, Pimpitak, Umaporn, Puthong, Songchan, Palaga, Tanapat, Komolpis, Kittinan   +5 more
openaire   +2 more sources