Results 91 to 100 of about 211,078 (328)

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

miR-371a-3p, miR-373-3p and miR-367-3p as Serum Biomarkers in Metastatic Testicular Germ Cell Cancers Before, During and After Chemotherapy

Cells, 2019
Background: LDH (lactate dehydrogenase), AFP (alpha-fetoprotein) and β-HCG (human chorionic gonadotropin) are used in diagnosis and follow-up of testicular germ cell cancer (TGCC) patients.
Ximena Rosas Plaza, Ton van Agthoven, Coby Meijer, Marcel A. T. M. van Vugt, Steven de Jong, Jourik A. Gietema, Leendert H. J. Looijenga   +6 more
doaj   +1 more source

Hepatocyte BPGM Induces RET Lactylation and Macrophage Reprogramming to Promote Tumorigenesis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Mechanistic schematic diagram.BPGM promotes the expression level of RET by increasing the lactylation of RET‐K549 and inhibiting its ubiquitination levels in HCC cells. Furthermore, BPGM in HCC cells could also promote M2 polarization in macrophages through lactate secretion. Both of the mechanisms could promote the progression of HCC. ABSTRACT Aerobic
Jiajia Zhang, Lu Shi, Liangliang Lin, Yang Zhang, Miao Zhang, Lili Wu, Yong Xia, Yaqiong Zhang, Peng Han, Likun Zhuang, Liang Shi   +10 more
wiley   +1 more source

Biochemical markers for prediction of hypertensive disorders of pregnancy [PDF]

Journal of Medical Biochemistry, 2019
Background: Gestational hypertension (GH) and preeclampsia (PE) are the most common gestational complications. Several placental biochemical markers are used to predict GH/PE, but with conflicting results.
Kocijančić-Belović Dusica, Plešinac Snežana, Dotlić Jelena, Savić-Radojević Ana, Akšam Slavica, Marjanović-Cvjetićanin Mirjana, Kocijančić Aleksandar   +6 more
doaj  

Development and Validation of a Prognostic Nomogram in AFP-negative hepatocellular carcinoma

International Journal on Biological Sciences, 2019
The aim of this study is to establish and validate an effective prognostic nomogram in patients with AFP-negative hepatocellular carcinoma (HCC). The nomogram was based on a primary cohort that consisted of 419 patients with clinicopathologically ...
Xueping Wang, M. Mao, Zhonglian He, Lin Zhang, Huilan Li, Jianhua Lin, Yimeng He, Shuqin Dai, Wanming Hu, Wanli Liu   +9 more
semanticscholar   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, Accepted Article.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

The use of biomarkers GP-73 and AFP in the early diagnosis of hepatocarcinoma associated with liver cirrhosis of HCV etiology

Журнал инфектологии
Purpose: comparative study of the informativeness of tumor markers GP-73 and AFP in the early diagnosis of hepatocellular carcinoma associated with liver cirrhosis of HCV etiology.Materials and methods: In the study, 71 people were divided into 4 groups.
A. K. Bayjanov, U. Yu. Ismоilov, A. S. Khikmatullaeva, Kh. P. Nasirova, J. A. Anvarov, Ch. B. Turaeva   +5 more
doaj   +1 more source

Module production of the one-arm AFP 3D pixel tracker

, 2016
The ATLAS Forward Proton (AFP) detector is designed to identify events in which one or two protons emerge intact from the LHC collisions. AFP will consist of a tracking detector, to measure the momentum of the protons, and a time of flight system to ...
Cavallaro, E., Chmeissani, M., Dorholt, O., Foerster, F., Grinstein, S., Lange, J., Manna, M., Paz, I. Lopez, Pellegrini, G., Quirion, D., Rijssenbeek, M., Rohne, O., Stugu, B.   +12 more
core   +1 more source

Suicide by Bomb, with Decapitation [PDF]

, 2016
Suicide by explosion is rare outside of the context of terrorist activities. We present a case of a man with a history of explosives expertise who committed suicide by bomb/decapitation.
McLemore, Amanda M., Prahlow, Joseph A., Prahlow, Samuel P.   +2 more
core   +1 more source