Results 121 to 130 of about 66,075 (218)

Resolving the apparent transmission paradox of African sleeping sickness.

PLoS Biology, 2019
Human African trypanosomiasis (HAT), or African sleeping sickness, is a fatal disease found throughout sub-Saharan Africa. The disease is close to elimination in many areas, although it was similarly close to elimination once before and subsequently ...
Paul Capewell, Katie Atkins, William Weir, Vincent Jamonneau, Mamadou Camara, Caroline Clucas, Nono-Raymond K Swar, Dieudonne M Ngoyi, Brice Rotureau, Paul Garside, Alison P Galvani, Bruno Bucheton, Annette MacLeod   +12 more
doaj   +1 more source

The elimination of Trypanosoma brucei gambiense? Challenges of reservoir hosts and transmission cycles: Expect the unexpected

Parasite Epidemiology and Control, 2019
The World Health Organisation has set the goal for elimination of Human African Trypanosomiasis (HAT), caused by Trypanosoma brucei gambiense (gHAT), as a public health problem for 2020 and for the total interruption of transmission to humans for 2030 ...
D. Mehlitz, D.H. Molyneux
doaj   +1 more source

Benefit-Cost Analysis and Socio-Economic Considerations of Trypanosomiasis Control and Treatment in Northern Ghana [PDF]

The paper estimates the cost of tsetse control and treatment of trypanosomiasis and the benefits involved, using benefit-cost analysis. It also estimates the extent to which socio-economic characteristics of farmers affect the use of tsetse control ...
Asuming-Brempong, Samuel, Wahab, S.
core   +1 more source

Mechanisms controlling anaemia in Trypanosoma congolense infected mice. [PDF]

, 2009
Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa.
A Kobayashi, A Shamseddine, AI Su, AJ Nok, Andy Brass, B Mertens, B Stijlemans, B Stijlemans, B Vanhollebeke, Birgit Rathkolb, BM Bolstad, C Beaumont, C Li, CA Facer, CA Schaer, Delnaz Roshandel, DM Wrighting, E Nemeth, E Nemeth, E Nemeth, Eckard Wolf, Fuad Iraqi, G Weiss, Gd Haan, Gordon Langsley, Harry A. Noyes, HC Greenblatt, Helen Hulme, Helmut Fuchs, HH Kazazian, J Naessens, J Naessens, J Naessens, J Naessens, Jan Naessens, JCM Trail, KAN Esievo, KC Corbit, LY Shih, M Murray, M Murray, M Shi, M Shi, M Sileghem, M Sileghem, Martin Hrabé de Angelis, Mohammad H. Alimohammadian, Morris Agaba, MR Rifkin, N Mabbott, O Van Assendaelft, PM Kristjanson, R Ferreira, RC Gregory, RH Wang, RKG Assoku, RM Ngure, S Kemp, S Kierstein, S Magez, S Magez, S Taniguchi, SH Goh, SJ Kemp, SK Moestrup, Stephen Kemp, T Sato, TC Cheng, Valerie Gailus-Durner, VO Anosa, W Morrison, W Morrison, W Zumkeller, Y Liang, Y Nakamura   +74 more
core   +3 more sources

Carmaphycin B-Based Proteasome Inhibitors to Treat Human African Trypanosomiasis: Structure–Activity Relationship and In Vivo Efficacy

ACS Infectious Diseases
The proteasome is essential for eukaryotic cell proteostasis, and inhibitors of the 20S proteasome are progressing preclinically and clinically as antiparasitics.
Lawrence J Liu, Karol R. Francisco, Yujie Uli Sun, M. S. M. Serafim, D. K. Amarasinghe, T. R. Teixeira, Bobby Lucero, Thales Kronenberger, Waad Elsayed, Hala Elwakeel, Momen Al-Hindy, J. Almaliti, William H. Gerwick, A. O'Donoghue, Conor R. Caffrey   +14 more
semanticscholar   +1 more source

Prevalence of Sodalis glossinidius and different trypanosome species in Glossina palpalis palpalis caught in the Fontem sleeping sickness focus of the southern Cameroon

Parasite, 2018
Tsetse flies are the cyclical vector of human and animal African trypanosomiasis. To improve vector control in order to achieve the elimination of human African trypanosomiasis (HAT) and boost the control of animal diseases, investigations have been ...
Kanté Tagueu Sartrien, Farikou Oumarou, Njiokou Flobert, Simo Gustave   +3 more
doaj   +1 more source

The trypanosomal transferrin receptor of trypanosoma brucei : a review [PDF]

, 2019
Iron is an essential element for life. Its uptake and utility requires a careful balancing with its toxic capacity, with mammals evolving a safe and bio-viable means of its transport and storage. This transport and storage is also utilized as part of the
Kariuki, Christopher K., Magez, Stefan, Stijlemans, Benoit   +2 more
core   +2 more sources

New insights from Gorongosa National Park and Niassa National Reserve of Mozambique increasing the genetic diversity of Trypanosoma vivax and Trypanosoma vivax-like in tsetse flies, wild ungulates and livestock from East Africa

Parasites & Vectors, 2017
Background Trypanosoma (Duttonella) vivax is a major pathogen of livestock in Africa and South America (SA), and genetic studies limited to small sampling suggest greater diversity in East Africa (EA) compared to both West Africa (WA) and SA.
Carla MF Rodrigues, Herakles A Garcia, Adriana C Rodrigues, André G Costa-Martins, Carlos L Pereira, Dagmar L Pereira, Zakaria Bengaly, Luis Neves, Erney P Camargo, Patrick B Hamilton, Marta MG Teixeira   +10 more
doaj   +1 more source

Deux projets régionaux de la FAO pour le développement de l'élevage dans les zones infestées par les glossines [PDF]

Tropicultura, 1987
Two FAO regional projects for livestock development in the tse-tse infested areas. In this paper, the authors present the objectives, activities, countries involved and inputs of two FAO Regional projects related to livestock development in tsetse ...
Hoste, C., Toure, SM.
doaj  

Domestic dogs as reservoirs for African trypanosomiasis in Mambwe district, eastern Zambia

Scientific Reports
The control of African trypanosomiasis (AT) in Eastern and Southern Africa, including Zambia, faces huge challenges due to the involvement of wild and domestic animal reservoirs.
Malimba Lisulo, B. Namangala, Cornelius Mweempwa, Maxwell Banda, Herman M Chambaro, L. Moonga, Hayashida Kyoko, Sugimoto Chihiro, K. Picozzi, Sutherland K. Maciver, E. MacLeod   +10 more
semanticscholar   +1 more source