Results 11 to 20 of about 66,075 (218)

Prevalence of Human and Animal African Trypanosomiasis in Nigeria: A Scoping Review

Parasitologia
African trypanosomiasis is a protozoan disease that affects both humans and animals. Human African Trypanosomiasis (HAT) is a Neglected Tropical Disease targeted for elimination in 2030.
Chinwe Chukwudi, Elizabeth Odebunmi, Chukwuemeka Ibeachu   +2 more
doaj   +4 more sources

REPRODUCTIVE ORGAN DAMAGE OF DOMESTIC RUMINANTS IN AFRICAN ANIMAL TRYPANOSOMIASIS: A REVIEW

FUDMA Journal of Agriculture and Agricultural Technology, 2022
Animal African trypanosomiasis affects both production and reproduction in domestic ruminants. The reproductive damages caused by trypanosomes have direct or indirect link to some specific organs like endocrine and pituitary gland which secrets follicle ...
A. Ajakaiye, M. A. Abdullahi, T. O. Olanrewaju   +2 more
semanticscholar   +2 more sources

Restricted insecticide application: a last mile control option for elimination of acute sleeping sickness and progressive control of African animal trypanosomiasis in South-Eastern Uganda [PDF]

BMC Veterinary Research
Background Animal African trypanosomiasis (AAT) poses a significant impediment to livestock production and economic progress in sub-Saharan Africa. To reduce the burden of AAT in Uganda and contribute to the AAT progressive control pathway, there is a ...
Dennis Muhanguzi, Auther Tamale Wasswa, Patrick P’Odyek Abila, Albert Mugenyi, Mesearch Kakuru, Harriet Abizera, Solomon Ainebyoona, Marvyn Kansiime, Wilson Amanyire, Joseph Nkamwesiga, Phillip Magambo Kimuda, Karla Rascón-García, Enock Matovu   +12 more
doaj   +2 more sources

African Animal Trypanosomiasis: A Systematic Review on Prevalence, Risk Factors and Drug Resistance in Sub-Saharan Africa

Journal of Medical Entomology, 2022
African animal trypanosomiasis (AAT) a parasitic disease of livestock in sub-Saharan Africa causing tremendous loses. Sub-Saharan continental estimation of mean prevalence in both large and small domestic animals, risk factors, tsetse and non-tsetse ...
Ivy Okello, E. Mafie, Gillian Eastwood, J. Nzalawahe, L. Mboera   +4 more
semanticscholar   +3 more sources

Interventions for Neglected Diseases Caused by Kinetoplastid Parasites: A One Health Approach to Drug Discovery, Development, and Deployment [PDF]

Pharmaceuticals
Kinetoplastids are protozoa that possess a unique organelle called a kinetoplast. These include the parasites Trypanosoma cruzi, T. brucei and related African trypanosomes, and Leishmania spp.
Godwin U. Ebiloma, Amani Alhejeli, Harry P. de Koning   +2 more
doaj   +2 more sources

Spatial distribution of African Animal Trypanosomiasis in Suba and Teso districts in Western Kenya [PDF]

BMC Research Notes, 2010
BackgroundStudies on the epidemiology of African Animal Trypanosomiasis (AAT) rarely consider the spatial dimension of disease prevalence. This problem is confounded by use of parasitological diagnostic methods of low sensitivity in field surveys.
S. M. Thumbi, J. Jung’a, R. Mosi, F. Mcodimba   +3 more
semanticscholar   +5 more sources

Expanding the applications of a bioluminescent mouse infection model of acute African trypanosomiasis

Frontiers in Chemical Biology
IntroductionIn vivo imaging technology based on bioluminescence has contributed to the study of different pathophysiological conditions involving inherited or transmissible diseases.
Diego Benítez, Cecilia Ortíz, Estefania Dibello, Estefania Dibello, Marcelo A. Comini   +4 more
doaj   +2 more sources

Novel Minor Groove Binders Cure Animal African Trypanosomiasis in an in Vivo Mouse Model. [PDF]

Journal of Medicinal Chemistry, 2019
Animal African trypanosomiasis (AAT) is a significant socioeconomic burden for sub-Saharan Africa because of its huge impact on livestock health. Existing therapies including those based on minor groove binders (MGBs), such as the diamidines, which have ...
Federica Giordani, A. Khalaf, K. Gillingwater, Jane C. Munday, H. D. de Koning, C. Suckling, M. Barrett, Fraser J. Scott   +7 more
semanticscholar   +5 more sources

Mathematical Model for Describing the Transmission of Animal African Trypanosomiasis in Cattle

Asian Research Journal of Mathematics
In this paper, we have formulated a mathematical model for the transmission dynamics of African Animal Trypanosomiasis (AAT) by incorporating spraying of the tsetse y population(vector) and treating the cattle population (host) as control strategies.
Conrad Akello, D. Ambogo, Richard Opiyo
semanticscholar   +2 more sources

Pharma to farmer: field challenges of optimizing trypanocide use in African animal trypanosomiasis. [PDF]

Trends in Parasitology, 2021
Trypanocides are a key control component of African animal trypanosomiasis (AAT) in tsetse-infested areas of sub-Saharan Africa. While farmers are dependent upon trypanocides, recent research highlights their inappropriate and ineffective use, problems with drug quality, and treatment failure.
Shauna Richards, L. Morrison, S. Torr, M. Barrett, Oliver Manangwa, F. Mramba, H. Auty   +6 more
semanticscholar   +5 more sources