Results 41 to 50 of about 66,075 (218)
Salivarian trypanosomes are extracellular parasites affecting humans, livestock and game animals. Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense are human infective sub-species of T.
Stefan Magez +3 more
doaj +1 more source
African Animal Trypanosomiasis (AAT), caused predominantly by Trypanosoma brucei brucei, T. vivax and T. congolense, is a fatal livestock disease throughout Sub-Saharan Africa. Treatment options are very limited and threatened by resistance.
Marzuq A. Ungogo +12 more
semanticscholar +1 more source
Insights from quantitative and mathematical modelling on the proposed 2030 goal for gambiense human African trypanosomiasis (gHAT) [PDF]
Gambiense human African trypanosomiasis (gHAT) is a parasitic, vector-borne neglected tropical disease that has historically affected populations across West and Central Africa and can result in death if untreated.
Aliee, Maryam +10 more
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African trypanosomiases are infectious diseases caused by trypanosomes. African animal trypanosomiasis (AAT) remains an important threat for livestock production in some affected areas whereas human African trypanosomiasis (HAT) is targeted for ...
Gustave Simo, Jean Baptiste Rayaisse
doaj +1 more source
Delineating neuroinflammation, parasite CNS invasion, and blood-brain barrier dysfunction in an experimental murine model of human African trypanosomiasis [PDF]
Although Trypanosoma brucei spp. was first detected by Aldo Castellani in CSF samples taken from sleeping sickness patients over a century ago there is still a great deal of debate surrounding the timing, route and effects of transmigration of the ...
Bradley, Barbara +2 more
core +1 more source
Animal African Trypanosomiasis: Time to Increase Focus on Clinically Relevant Parasite and Host Species [PDF]
Animal African trypanosomiasis (AAT), caused by Trypanosoma congolense and Trypanosoma vivax, remains one of the most important livestock diseases in sub-Saharan Africa, particularly affecting cattle. Despite this, our detailed knowledge largely stems from the human pathogen Trypanosoma brucei and mouse experimental models.
Morrison, Liam +3 more
openaire +3 more sources
Background: Human and animal African trypanosomiases impose a large economic and health burden in their endemic regions. Large strides have been made in the control of human African trypanosomiasis (HAT), yet these efforts have largely focused on the non-
Julianne Meisner +2 more
doaj +1 more source
Nanobodies as tools to understand, diagnose, and treat African trypanosomiasis [PDF]
African trypanosomes are strictly extracellular protozoan parasites that cause diseases in humans and livestock and significantly affect the economic development of sub-Saharan Africa.
Caljon, Guy +5 more
core +1 more source
In Vitro Mechanism of Action of Acanthospermum hispidum in Trypanosoma brucei
African trypanosomiasis is a major neglected tropical disease with significant health and economic concerns in sub-Saharan Africa. In the absence of vaccines for African trypanosomiasis, there is a consideration for alternative sources of chemotherapy ...
Aboagye Kwarteng Dofuor +4 more
doaj +1 more source
African animal trypanocide resistance: A systematic review and meta-analysis
Background African animal trypanocide resistance (AATr) continues to undermine global efforts to eliminate the transmission of African trypanosomiasis in endemic communities. The continued lack of new trypanocides has precipitated drug misuse and overuse,
K. I. Kasozi, E. MacLeod, S. Welburn
semanticscholar +1 more source

