Results 131 to 140 of about 70,035 (260)

Newcastle Disease Virus-Vectored African Swine Fever Virus Antigen Cocktail Delays the Onset of ASFV-SY18 but Is Not Protective

Microorganisms
African Swine Fever (ASF) is a highly contagious viral disease threatening the global pig industry. Currently, only two gene-deleted live attenuated vaccines are approved, exclusively in Vietnam, and their long-term effectiveness and safety are unproven,
Qian Li, Yiqian Jiang, Min Zheng, Xuefei Sun, Lili Hui, Yanyan Zhang, Huixian Yue, Yu Qi, Siqi Li, Junnan Ke, Qixuan Li, Boli Ma, Xiaoying Jia, Fengjie Wang, Lijuan Mi, Shoufeng Zhang, Faming Miao, Shuchao Wang, Fei Zhang, Teng Chen, Rongliang Hu   +20 more
doaj   +1 more source

Fully Synthetic Non‐Carbohydrate Heparin Mimetics—Perspectives for Therapeutic Anticoagulation and Beyond?

Archiv der Pharmazie, Volume 359, Issue 4, April 2026.
Fully synthetic sulfated non‐carbohydrate polymers for structurally mimicking the polysaccharide glycosaminoglycan heparin in its anticoagulant activities with further prospects to pleiotropic effects in oncology and in antiviral approaches. ABSTRACT Heparin is one of the oldest drugs on the market.
Katrin Nekipelov, Vito Ferro, Gerd Bendas   +2 more
wiley   +1 more source

Mpox in South Asia: A Narrative Review on Epidemiology, Preparedness, and Preventive Strategies

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Monkeypox (Mpox), due to its growing global concern, was declared a public health emergency of worldwide concern by the World Health Organization in August 2024. The monkeypox virus (MPXV), once limited to African regions, has now spread to South Asia, including Pakistan, India, Nepal, and Sri Lanka, and there have been ...
Jannatul Mawa, Shariun Nahar Rimun, Nujhat Zayma Rahman, Mohiuddin Ahmed Bhuiyan, Mohammad Shahriar, Ramisa Anjum   +5 more
wiley   +1 more source

Pseudorabies virus DNA polymerase processivity factor pUL42 inhibits type I IFN production by negatively regulating cGAS-STING signaling pathway

Journal of Virology
Pseudorabies (PR), caused by the PR virus (PRV), is an acute infectious disease in livestock and various wild animals. PRV has developed several immune evasion mechanisms to antagonize the host’s antiviral immune response.
Guangqiang Ye, Jiaxiu Gao, Haoxuan Cao, Xiaohong Liu, Hongyang Liu, Shanghui Wang, Yunfei Liu, Longfei Han, Qiongqiong Zhou, Yandong Tang, Jin Tian, Liping Huang, Li Huang, Zhaoxia Zhang, Changjiang Weng   +14 more
doaj   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Exploiting textual source information for epidemiosurveillance [PDF]

, 2014
In recent years as a complement to the traditional surveillance reporting systems there is a great interest in developing methodologies for early detection of potential health threats from unstructured text present on the Internet.
Arsevska, Elena, Dufour, Barbara, Hendrikx, Pascal, Lancelot, Renaud, Roche, Mathieu   +4 more
core   +1 more source

Simultaneous Detection of Classical and African Swine Fever Viruses by Duplex Taqman Real-Time PCR Assay in Pigs Infected with Both Diseases

Pathogens
The increasing spread of African swine fever (ASF) in recent years and the presence of classical swine fever (CSF) subclinical forms in endemic countries suggests that the possibility of coinfection with ASF virus (ASFV) and CSF virus (CSFV) in pigs ...
Liani Coronado, Adriana Muñoz-Aguilera, Miaomiao Wang, Iván Muñoz, Cristina Riquelme, Saray Heredia, Katarzyna Stępniewska, Carmina Gallardo, Llilianne Ganges   +8 more
doaj   +1 more source

African swine fever.

The Onderstepoort journal of veterinary research, 2009
African swine fever (ASF) is a devastating haemorrhagic fever of pigs that causes up to 100% mortality, for which there is no vaccine. It is caused by a unique DNA virus that is maintained in an ancient cycle between warthogs and argasid ticks, making it the only known DNA arbovirus. ASF has a high potential for transboundary spread, and has twice been
openaire   +2 more sources

Deletion of the B125R gene in the African swine fever virus SY18 strain leads to an A104R frameshift mutation slightly attenuating virulence in domestic pigs

Virus Research
African swine fever (ASF), caused by the ASF virus (ASFV), is a hemorrhagic and fatal viral disease that affects Eurasian wild boars and domestic pigs, posing a substantial threat to the global pig breeding industry.
Rongnian Zhu, Ying Wang, Han Zhang, Jinjin Yang, Jiaqi Fan, Yanyan Zhang, Yu Wang, Qixuan Li, Xintao Zhou, Huixian Yue, Yu Qi, Shuchao Wang, Teng Chen, Shoufeng Zhang, Rongliang Hu   +14 more
doaj   +1 more source

Cholesterol affects African swine fever virus infection [PDF]

, 1989
African swine fever virus (ASFV) enters cells by receptor mediated endocytosis and requires a fusion event between the viral envelope and the limiting membrane of the endosome at low pH. In order to investigate the role of cholesterol in the early stages
Bernardes, C., António, A., Pedroso de Lima, Maria C., Valdeira, M. L.   +3 more
core   +1 more source