Results 41 to 50 of about 44,463 (262)

A Triplex PCR Method for Distinguishing the Wild-Type African Swine Fever Virus From the Deletion Strains by Detecting the Gene Insertion

Frontiers in Veterinary Science, 2022
To date, there is no effective vaccine or antiviral therapy available to prevent or treat African swine fever virus (ASFV) infections. ASFV gene deletion strains have been proposed as promising anti-ASFV vaccine candidates.
Zhao Huang, Zhao Huang, Zhiying Xu, Zhiying Xu, Haoxuan Cao, Haoxuan Cao, Fanliang Zeng, Fanliang Zeng, Heng Wang, Heng Wang, Heng Wang, Lang Gong, Lang Gong, Shengxun Zhang, Sen Cao, Guihong Zhang, Guihong Zhang, Guihong Zhang, Guihong Zhang, Zezhong Zheng, Zezhong Zheng   +20 more
doaj   +1 more source

African Swine Fever Virus H240R Protein Inhibits the Production of Type I Interferon through Disrupting the Oligomerization of STING

Journal of Virology, 2023
African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious and acute hemorrhagic viral disease with a high mortality, approaching 100% in domestic pigs.
Guangqiang Ye, Hongyang Liu, Xiaohong Liu, Wei-ye Chen, Jiangnan Li, Dongmin Zhao, G. Wang, Chun-ling Feng, Zhaoxia Zhang, Qiongqiong Zhou, Jun Zheng, Z. Bu, C. Weng, Li Huang   +13 more
semanticscholar   +1 more source

African Swine Fever Virus Envelope Glycoprotein CD2v Interacts with Host CSF2RA to Regulate the JAK2-STAT3 Pathway and Inhibit Apoptosis to Facilitate Virus Replication

Journal of Virology, 2023
African swine fever is a hemorrhagic disease caused by the African swine fever virus (ASFV), which infects pigs of different breeds and ages, with a fatality rate of up to 100%.
Qi Gao, Yunlong Yang, Yizhuo Luo, Xiong-nan Chen, Ting Gong, Dongdong Wu, Yongzhi Feng, Xiaoyu Zheng, Heng Wang, Guihong Zhang, G. Lu, L. Gong   +11 more
semanticscholar   +1 more source

Identification and characterization of nanobodies specifically against African swine fever virus major capsid protein p72

Frontiers in Microbiology, 2022
African swine fever virus (ASFV) is a large and very complex DNA virus. The major capsid protein p72 is the most predominant structural protein and constitutes the outmost icosahedral capsid of the virion.
Jifei Yang, Mengyao Jing, Qingli Niu, Jinming Wang, Yaru Zhao, Yaru Zhao, Meng Liu, Guiquan Guan, Jianxun Luo, Hong Yin, Hong Yin, Zhijie Liu, Zhijie Liu   +12 more
doaj   +1 more source

Riding apoptotic bodies for cell–cell transmission by African swine fever virus

Proceedings of the National Academy of Sciences of the United States of America, 2023
Significance ASFV is a leading threat to the world pork production and has evolved a mechanism to avoid antibody neutralization, contributing to viral persistence within infected pigs. We report here that ASFV highjacks the cellular efferocytosis pathway
Peng Gao, Lei Zhou, Jiajun Wu, Wenlian Weng, Hua Wang, Miaomiao Ye, Yajin Qu, Yuxin Hao, Yongning Zhang, X. Ge, Xin Guo, Jun Han, Hanchun Yang   +12 more
semanticscholar   +1 more source

African Swine Fever in Cameroon: A Review [PDF]

Pathogens, 2021
African swine fever (ASF) is a hemorrhagic contagious porcine disease caused by the African swine fever virus. The disease poses enormous problems to the pork industry with pig mortality ranging from 30% to 100%, depending on the virulence of the virus circulating.
Ebanja Joseph Ebwanga, Stephen Mbigha Ghogomu, Jan Paeshuyse   +2 more
openaire   +4 more sources

African swine fever control and prevention: an update on vaccine development

Emerging Microbes and Infections, 2022
African swine fever (ASF) is a lethal and highly contagious viral disease of domestic and wild pigs, listed as a notifiable disease reported to the World Organization for Animal Health (OIE).
A. Urbano, F. Ferreira
semanticscholar   +1 more source

Epidemiological analyses of African swine fever in the European Union

EFSA journal. European Food Safety Authority, 2022
This report provides a descriptive analysis of the African swine fever (ASF) Genotype II epidemic in the affected Member States in the EU and two neighbouring countries for the period from 1 September 2020 to 31 August 2021.
Joaquín Vicente Baños, A. Boklund, A. Gogin, C. Gortázar, V. Gubertì, Georgina Helyes, M. Kantere, Daniela Korytarova, A. Linden, M. Masiulis, A. Miteva, I. Neghirla, E. Oļševskis, S. Ostojić, Satran Petr, C. Staubach, H. Thulke, A. Viltrop, G. Woźniakowski, A. Broglia, José Abrahantes Cortiñas, S. Dhollander, L. Mur, A. Papanikolaou, Y. Van der Stede, G. Zancanaro, K. Ståhl   +26 more
semanticscholar   +1 more source

Spatiotemporally Orchestrated Interactions between Viral and Cellular Proteins Involved in the Entry of African Swine Fever Virus

Viruses, 2021
African swine fever (ASF) is a highly contagious hemorrhagic disease in domestic pigs and wild boars with a mortality of up to 100%. The causative agent, African swine fever virus (ASFV), is a member of the Asfarviridae family of the nucleocytoplasmic ...
Kehui Zhang, Su Li, Sheng Liu, Shuhong Li, Liang Qu, George F. Gao, Hua-Ji Qiu   +6 more
doaj   +1 more source

Swine Interferon-Inducible Transmembrane Proteins Potently Inhibit African Swine Fever Virus Replication

Frontiers in Immunology, 2022
African swine fever virus (ASFV) causes an acute, hemorrhagic, and highly contagious disease in domestic swine, leading to significant economic losses to the global porcine industry.
Siqi Cai, Siqi Cai, Siqi Cai, Zezhong Zheng, Zezhong Zheng, Zezhong Zheng, JiaoJiao Cheng, JiaoJiao Cheng, JiaoJiao Cheng, Lintao Zhong, Lintao Zhong, Lintao Zhong, Ran Shao, Ran Shao, Ran Shao, Feiyan Zheng, Feiyan Zheng, Feiyan Zheng, Zhiying Lai, Zhiying Lai, Zhiying Lai, Jiajun Ou, Jiajun Ou, Jiajun Ou, Liang Xu, Liang Xu, Liang Xu, Pei Zhou, Pei Zhou, Pei Zhou, Gang Lu, Gang Lu, Gang Lu, Guihong Zhang, Guihong Zhang, Guihong Zhang   +35 more
doaj   +1 more source