Results 61 to 70 of about 8,035 (213)

A Mathematical Model that Simulates Control Options for African Swine Fever Virus (ASFV)

PLOS ONE, 2016
A stochastic model designed to simulate transmission dynamics of African swine fever virus (ASFV) in a free-ranging pig population under various intervention scenarios is presented. The model was used to assess the relative impact of the timing of the implementation of different control strategies on disease-related mortality.
Mike B. Barongo, Richard P. Bishop, Eric M. Fèvre, Darryn L. Knobel, Amos Ssematimba   +4 more
openaire   +5 more sources

Novel method for sub‐grouping of genotype II African swine fever viruses based on the intergenic region between the A179L and A137R genes

Veterinary Medicine and Science, 2022
Background African swine fever (ASF) is a highly contagious and deadly viral disease affecting domestic and wild pigs of all ages. African swine fever virus (ASFV) has spread rapidly through Eastern and Southeastern Asia first appearing in Vietnam in ...
Ha Thi Thanh Tran, Anh Duc Truong, Anh Kieu Dang, Duc Viet Ly, Nhu Thi Chu, Tuan Van Hoang, Huyen Thi Nguyen, Christopher L Netherton, Hoang Vu Dang   +8 more
doaj   +1 more source

African swine fever virus MGF-360-10L is a novel and crucial virulence factor that mediates ubiquitination and degradation of JAK1 by recruiting the E3 ubiquitin ligase HERC5

mBio, 2023
African swine fever virus (ASFV) causes acute hemorrhagic infectious disease in pigs. The ASFV genome encodes various proteins that enable the virus to escape innate immunity; however, the underlying mechanisms are poorly understood.
Dan Li, Jiangling Peng, Junhuang Wu, Jiamin Yi, Panxue Wu, Xiaolan Qi, Jingjing Ren, Gaochuang Peng, Xianghan Duan, Yi Ru, Huanan Liu, Hong Tian, Haixue Zheng   +12 more
doaj   +1 more source

An attenuated African swine fever virus expressing the E2 glycoprotein of classical swine fever virus protects pigs against challenge of both viruses

Emerging Microbes and Infections
African swine fever (ASF) and classical swine fever (CSF) are highly contagious diseases with high morbidity and mortality rates resulting in an enormous impact on the global pig industry.
Jiwen Zhang, Fang Li, Weiye Chen, Yongfeng Li, Zhenjiang Zhang, Ronghong Hua, Renqiang Liu, Yuanmao Zhu, Encheng Sun, Huaji Qiu, Zhigao Bu, Dongming Zhao   +11 more
doaj   +1 more source

Attempts at the development of a recombinant African swine fever virus strain with abrogated EP402R, 9GL, and A238L gene structure using the CRISPR/Cas9 system

Journal of Veterinary Research, 2020
African swine fever (ASF) is a pressing economic problem in a number of Eastern European countries. It has also depleted the Chinese sow population by 50%.
Woźniakowski Grzegorz, Mazur-Panasiuk Natalia, Walczak Marek, Juszkiewicz Małgorzata, Frant Maciej, Niemczuk Krzysztof   +5 more
doaj   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Structure and function of African swine fever virus proteins: Current understanding

Frontiers in Microbiology, 2023
African swine fever virus (ASFV) is a highly infectious and lethal double-stranded DNA virus that is responsible for African swine fever (ASF). ASFV was first reported in Kenya in 1921.
Sicheng Yang, Chun Miao, Wei Liu, Guanglei Zhang, Junjun Shao, Huiyun Chang   +5 more
doaj   +1 more source

Digital Point‐of‐Care Testing Device Based on Bioluminescent Pyrophosphate in Real‐Time and Recombinase‐aid Amplification

Advanced Intelligent Systems, Volume 8, Issue 3, March 2026.
A point‐of‐care testing method based on solvent‐responsive magnetic beads suitable for large‐area diagnosis and mutation screening in remote areas was developed to detect it by combining bioluminescenct pyrophosphate in real‐time technology and recombinase‐aid amplification technology.
Zhongjie Fei, Juan Bai, Liwei Xu, Siyi Wang, Pengfeng Xiao, Dongrui Zhou, Guanxiong Liu, Rongbin Wei, Ping Jiang   +8 more
wiley   +1 more source

MGF360-9L Is a Major Virulence Factor Associated with the African Swine Fever Virus by Antagonizing the JAK/STAT Signaling Pathway

mBio, 2022
African swine fever (ASF)—an aggressive infectious disease caused by the African swine fever virus (ASFV)—is significantly unfavorable for swine production. ASFV has a complex structure and encodes 150–167 proteins; however, the function of most of these
Keshan Zhang, Bo Yang, Chaochao Shen, Ting Zhang, Yu Hao, Dajun Zhang, Huanan Liu, Xijuan Shi, Guoli Li, Jinke Yang, Dan Li, Zixiang Zhu, Hong Tian, Fan Yang, Yi Ru, Wei Jun Cao, Jianhong Guo, Jijun He, Haixue Zheng, Xiangtao Liu   +19 more
doaj   +1 more source

Two African swine fever virus proteins derived from a common precursor exhibit different nucleocytoplasmic transport activities [PDF]

, 2004
African swine fever virus (ASFV), a large icosahedral deoxyvirus, is the causative agent of an economically relevant hemorrhagic disease that affects domestic pigs.
Eulálio, A., Nunes-Correia, I., Carvalho, A. L., Faro, C., Citovsky, V., Simões, S., Lima, M. C. Pedroso de   +6 more
core   +1 more source