Results 81 to 90 of about 2,737,561 (202)

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, Volume 73, Issue 9, Page 1291-1306, September 2026.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

Cryo-electron tomography of isolated african swine fever virus (ASFV)

, 2022
African swine fever virus (ASFV) is a large nucleocytoplasmic DNA virus that shares the icosahedrical symmetry of iridoviruses and the complex genomic organization of the poxvirus, and it is actually the only member of the Asfaviridae family[1]. A common feature in these viral groups is that they are formed by several complex envelopes that have been ...
Chichón, Francisco Javier, Rodríguez, María Josefa, Castón, José R., Salas Falgueras, María Luisa, Carrascosa, Ángel L., Carrascosa, José L.   +5 more
openaire   +1 more source

Quantitative proteomic analysis identifies the unfolded protein response as a host pathway co-opted by ASFV to promote replication

mBio
African swine fever (ASF), caused by the African swine fever virus (ASFV), is a highly contagious disease that affects pigs, resulting in substantial economic losses in the global pig industry.
Danyang Zhang, Baohong Liu, Huanan Liu, Ruoqing Mao, Weijun Cao, Xiangle Zhang, Fayu Yang, Yichao Wang, Chaochao Shen, Shilei Zhang, Zixiang Zhu, Haixue Zheng   +11 more
doaj   +1 more source

Neuronal Apoptotic Bodies Facilitate Japanese Encephalitis Virus Infection and Pathogenicity

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Japanese encephalitis (JE) caused by Japanese encephalitis virus (JEV) infection remains one of the major types of viral encephalitis. The mechanisms underlying JEV infection and pathogenesis have not been fully elucidated, resulting in the absence of specific therapies for JE. Neuronal apoptosis is a well‐established outcome of JEV infection;
Chuan Zeng, Xiaowei Nan, Ting Wang, Junyao Xiong, Shuo Zhu, Chengjie Yang, Bibo Zhu, Youhui Si, Shengbo Cao, Jing Ye   +9 more
wiley   +1 more source

African Swine Fever Virus (Asfv) Multigene Families 360 and 530 Genes Promote Infected Macrophage Survival [PDF]

The Scientific World JOURNAL, 2001
INTRODUCTION. In the swine host ASFV infects cells of the mononuclear-phagocytic system including fixed tissue macrophages (1). Cytopathological changes consistent with apoptotic cell death, including karyorrhexis and chromatin condensation, have been observed in mononuclear cells in tissues of pigs infected with highly virulent ASFV isolates (2). ASFV
L. Zsak, J.H. Sur, T.G. Burrage, J.G. Neilan, D.L. Rock   +4 more
openaire   +3 more sources

The S273R protein of African swine fever virus antagonizes the canonical NF-κB signaling pathway by IκBα

Journal of Virology
African swine fever virus (ASFV) is a large double-stranded DNA virus, which is the causative agent of African swine fever (ASF), a devastating disease of suids epidemic in many countries. The virus has developed multiple strategies to evade surveillance
Haojie Ren, Lan-Fang Shi, Yanjin Wang, Xiao-Ya Pan, Su Li, Yu-He Ma, Jun-Hao Fan, Xing Chen, Zhong-Yuan Yang, Shuai Fan, Yuhang Zhang, Shichong Han, Wen-Rui He, Bo Wan, Hua-Ji Qiu, Gai-Ping Zhang   +15 more
doaj   +1 more source

Machine‐Learning Microfluidic Minute‐Scale Microorganism Metrics Monitoring(M6)

Advanced Science, Volume 13, Issue 37, 3 July 2026.
ABSTRACT On‐site monitoring of microorganisms remains challenging because of low concentrations, strong background interference, and dynamic aerosol diffusion, particularly for aerosol‐transmitted pathogens. Here, we report a rapid detection platform that integrates a Puri‐focusing microfluidic chip, electrochemical impedance spectroscopy (EIS), and ...
Ning Yang, Jiahao Ding, Si Chen, Lijie Yan, Shichao Ding, Lavonda Li, Junyi Sun, Haodong Liu, Tongge Li, Ning Liu, Mingji Wei, Xiaoyong Zhu, Xiaobo Zou, Shouqi Yuan, Xingcai Zhang   +14 more
wiley   +1 more source

Testing multiplexed anti-ASFV CRISPR-Cas9 in reducing African swine fever virus

Microbiology Spectrum
ABSTRACT African swine fever (ASF) is a highly fatal viral disease that poses a significant threat to domestic pigs and wild boars globally. In our study, we aimed to explore the potential of a multiplexed CRISPR-Cas system in suppressing ASFV replication and infection.
Zezhong Zheng, Lei Xu, Yangbin Gao, Hongwei Dou, Yixuan Zhou, Xu Feng, Xiangjun He, Zhen Tian, Lingling Song, Guolong Mo, Jiapan Hu, Hongye Zhao, Hongjiang Wei, George M. Church, Luhan Yang   +14 more
openaire   +3 more sources

African swine fever virus hijacks host pyrimidine metabolism to promote viral replication

Journal of Virology
African swine fever (ASF) is a highly contagious disease of pigs caused by the African swine fever virus (ASFV), posing a significant threat to global swine production.
Zebu Song, Yilin Chen, Hui Guo, Guihong Zhang, Lang Gong, Zezhong Zheng   +5 more
doaj   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, Volume 13, Issue 34, 19 June 2026.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source