Results 61 to 70 of about 2,737,561 (202)

Attempts at the development of a recombinant African swine fever virus strain with abrogated EP402R, 9GL, and A238L gene structure using the CRISPR/Cas9 system

Journal of Veterinary Research, 2020
African swine fever (ASF) is a pressing economic problem in a number of Eastern European countries. It has also depleted the Chinese sow population by 50%.
Woźniakowski Grzegorz, Mazur-Panasiuk Natalia, Walczak Marek, Juszkiewicz Małgorzata, Frant Maciej, Niemczuk Krzysztof   +5 more
doaj   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, Volume 13, Issue 57, 14 October 2026.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Complete Genome Sequence of a Virulent African Swine Fever Virus from a Domestic Pig in Ukraine. [PDF]

, 2019
Here, we report the complete genome sequence of an African swine fever (ASF) virus (ASFV/Kyiv/2016/131) isolated from the spleen of a domestic pig in Ukraine with a lethal case of African swine fever. Using only long-read Nanopore sequences, we assembled
Redlinger, Matthew, Nychyk, Serhiy, Frant, Maciej, Solodiankin, Oleksii, Ishchenko, Liudmyla, Drown, Devin, Lange, Christian, Bortz, Eric, Dubchak, Inna, Bezymennyi, Maksym, Sapachova, Maryna, Ducluzeau, Anne-Lise, Sushko, Mykola, Dagdag, Ralf, Mezhenskyi, Andrii, Kovalenko, Ganna, Gerilovych, Anton, Rudova, Nataliia   +17 more
core   +1 more source

Structure and function of African swine fever virus proteins: Current understanding

Frontiers in Microbiology, 2023
African swine fever virus (ASFV) is a highly infectious and lethal double-stranded DNA virus that is responsible for African swine fever (ASF). ASFV was first reported in Kenya in 1921.
Sicheng Yang, Chun Miao, Wei Liu, Guanglei Zhang, Junjun Shao, Huiyun Chang   +5 more
doaj   +1 more source

FAM134B Restricts African Swine Fever Virus Capsid Assembly via Reticulophagy and Its Antiviral Activity is Antagonized by the Viral Virulence‐Associated Factor pMGF300‐2R

Advanced Science, Volume 13, Issue 58, 19 October 2026.
ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral activity against multiple RNA ...
Rui Luo, Jing Zhang, Ruojia Huang, Xianfeng Zhang, Lian‐Feng Li, Jing Lan, Zhanhao Lu, Yuan Sun, Tao Wang, Hua‐Ji Qiu   +9 more
wiley   +1 more source

African swine fever virus (ASFV) in Poland: Prevalence in a wild boar population (2017-2018) [PDF]

Veterinární medicína, 2020
African swine fever (ASF) was first described in 1921 in Kenya. The latest epidemic of ASF started in 2007 in Georgia. The virus was introduced to Poland in 2014. Since the beginning of the epidemics, the National Veterinary Research Institute in Pulawy (NVRI) has been testing wild boar samples from restricted areas and other parts of Poland to conduct
Maciej Frant, Magdalena Lyjak, Lukasz Bocian, Anna Barszcz, Krzysztof Niemczuk, Grzegorz Wozniakowski   +5 more
openaire   +2 more sources

Transmission of African swine fever virus to the wild boars of Northeast India

Veterinary Quarterly, 2023
Background India recorded the first outbreak of African swine fever (ASF) in North-eastern region (NER) in the year 2020.Aim The current study was undertaken to investigate the transmission of African swine fever virus (ASFV) in the wild boars of ...
Lukumoni Buragohain, Nagendra Nath Barman, Suparna Sen, Arpita Bharali, Biswajit Dutta, Bhaskar Choudhury, Kuralayanapalya Puttahonnappa Suresh, Shubham Gaurav, Rakesh Kumar, Samshul Ali, Sachin Kumar, Yashpal Singh Malik   +11 more
doaj   +1 more source

Alveolar Macrophages: Development, Respiratory Homeostasis, Signal Pathways, Diseases, and Therapeutic Opportunities

MedComm, Volume 7, Issue 10, October 2026.
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang, Ruomeng Li, Chuanjiang Yu, Jing Li, Xikun Zhou   +4 more
wiley   +1 more source

MGF360-9L Is a Major Virulence Factor Associated with the African Swine Fever Virus by Antagonizing the JAK/STAT Signaling Pathway

mBio, 2022
African swine fever (ASF)—an aggressive infectious disease caused by the African swine fever virus (ASFV)—is significantly unfavorable for swine production. ASFV has a complex structure and encodes 150–167 proteins; however, the function of most of these
Keshan Zhang, Bo Yang, Chaochao Shen, Ting Zhang, Yu Hao, Dajun Zhang, Huanan Liu, Xijuan Shi, Guoli Li, Jinke Yang, Dan Li, Zixiang Zhu, Hong Tian, Fan Yang, Yi Ru, Wei Jun Cao, Jianhong Guo, Jijun He, Haixue Zheng, Xiangtao Liu   +19 more
doaj   +1 more source

Glutamine Metabolism in Health and Diseases

MedComm, Volume 7, Issue 10, October 2026.
Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding, Fan Tong, Jing Zeng, Chun‐Ping Cui   +3 more
wiley   +1 more source