Results 81 to 90 of about 8,035 (213)

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen, Yang Liu, Congyang Du, Shengguo Gao, Lufeng Zhai, Stefan Schwarz, Weicheng Liu, Qiong Li, Longyu Li, Runhao Yu, Yuzhe Zhao, Hong Yao, Lei Luo, Xue Liu, Chunyan Xu, Xiang-Dang Du, Zongfu Wu   +16 more
wiley   +1 more source

Identification of a Continuously Stable and Commercially Available Cell Line for the Identification of Infectious African Swine Fever Virus in Clinical Samples

Viruses, 2020
African swine fever virus (ASFV) is causing outbreaks both in domestic pigs and wild boar in Europe and Asia. In 2018, the largest pig producing country, China, reported its first outbreak of African swine fever (ASF). Since then, the disease has quickly
Ayushi Rai, Sarah Pruitt, Elizabeth Ramirez-Medina, Elizabeth A. Vuono, Ediane Silva, Lauro Velazquez-Salinas, Consuelo Carrillo, Manuel V. Borca, Douglas P. Gladue   +8 more
doaj   +1 more source

Pathology of porcine peripheral white blood cells during infection with African swine fever virus [PDF]

, 2012
Background African swine fever virus (ASFV) is the causative agent of African swine fever (ASF) that is the significant disease of domestic pigs. Several studies showed that ASFV can influence on porcine blood cells in vitro.
Zaven Karalyan, Hovakim Zakaryan, Hranush Arzumanyan, Khachik Sargsyan, Henrik Voskanyan, Lina Hakobyan, Liana Abroyan, Aida Avetisyan, Elena Karalova   +8 more
core   +2 more sources

Emerging Challenges and Advances in Porcine Circovirus: A Decade in Review

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Over the past decade, porcine circoviruses (PCVs) have continued to pose a significant threat to global swine health, and pivotal discoveries have significantly reshaped our understanding of their biology and control. Extensive genomic surveillance has expanded porcine circovirus 2 (PCV2) genotyping from four to at least eight lineages, with PCV2d now ...
Jiawei Zheng, Guoqing Zhang, Peiheng Li, Linzhu Ren, Nan-hua Chen   +4 more
wiley   +1 more source

The CP123L protein of African swine fever virus is a membrane-associated, palmitoylated protein required for viral replication

Journal of Virology
African swine fever (ASF) is a highly contagious and often lethal disease caused by African swine fever virus (ASFV) in pigs. Protein palmitoylation is a prevalent posttranslational lipid modification that can modulate viral replication.
Xiangyu Guan, Tao Wang, Yuxuan Gao, Huanjie Zhai, Fengwei Jiang, Qinghe Hou, Xiaoke Yang, Hongxia Wu, Lian-Feng Li, Yuzi Luo, Su Li, Yuan Sun, Hua-Ji Qiu, Yongfeng Li   +13 more
doaj   +1 more source

ASFV-G-∆I177L as an Effective Oral Nasal Vaccine against the Eurasia Strain of Africa Swine Fever

Viruses, 2021
The African swine fever virus (ASFV) is currently causing a pandemic affecting wild and domestic swine from Western Europe to Asia. No commercial vaccines are available to prevent African swine fever (ASF), resulting in overwhelming economic losses to ...
Manuel V. Borca, Elizabeth Ramirez-Medina, Ediane Silva, Elizabeth Vuono, Ayushi Rai, Sarah Pruitt, Nallely Espinoza, Lauro Velazquez-Salinas, Cyril G. Gay, Douglas P. Gladue   +9 more
doaj   +1 more source

Isolation and Pathogenicity of a Getah Virus With a Novel Deletion in the 3′ UTR

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The spread of Getah virus (GETV) in China has become increasingly severe due to long‐term neglect and the lack of vaccines, posing a threat to animal safety and public health. In this study, we isolated and identified a novel GETV strain, designated GETV‐CX7.
Yawei Sun, Haiyan Li, Wenxu Wang, Yaqing Shi, Dongzhuo Yang, Yingshuo Zhang, Jimei Du, Yongtao Li, Linyang Yu, Xianfeng Zhang, Lu Chen, Zu Zhang Wei   +11 more
wiley   +1 more source

Quantitative proteomic analysis identifies the unfolded protein response as a host pathway co-opted by ASFV to promote replication

mBio
African swine fever (ASF), caused by the African swine fever virus (ASFV), is a highly contagious disease that affects pigs, resulting in substantial economic losses in the global pig industry.
Danyang Zhang, Baohong Liu, Huanan Liu, Ruoqing Mao, Weijun Cao, Xiangle Zhang, Fayu Yang, Yichao Wang, Chaochao Shen, Shilei Zhang, Zixiang Zhu, Haixue Zheng   +11 more
doaj   +1 more source

Evaluation in Swine of a Recombinant African Swine Fever Virus Lacking the MGF-360-1L Gene

Viruses, 2020
The African swine fever (ASF) pandemic is currently affecting pigs throughout Eurasia, resulting in significant swine production losses. The causative agent, ASF virus (ASFV), is a large, structurally complex virus with a genome encoding more than 160 ...
Elizabeth Ramirez-Medina, Elizabeth A. Vuono, Ayushi Rai, Sarah Pruitt, Ediane Silva, Lauro Velazquez-Salinas, James Zhu, Douglas P. Gladue, Manuel V. Borca   +8 more
doaj   +1 more source

The S273R protein of African swine fever virus antagonizes the canonical NF-κB signaling pathway by IκBα

Journal of Virology
African swine fever virus (ASFV) is a large double-stranded DNA virus, which is the causative agent of African swine fever (ASF), a devastating disease of suids epidemic in many countries. The virus has developed multiple strategies to evade surveillance
Haojie Ren, Lan-Fang Shi, Yanjin Wang, Xiao-Ya Pan, Su Li, Yu-He Ma, Jun-Hao Fan, Xing Chen, Zhong-Yuan Yang, Shuai Fan, Yuhang Zhang, Shichong Han, Wen-Rui He, Bo Wan, Hua-Ji Qiu, Gai-Ping Zhang   +15 more
doaj   +1 more source