Results 1 to 10 of about 11,478 (246)

Immune Thrombocytopenia in an Adult With X‐linked Agammaglobulinemia: A Case Report [PDF]

open access: yeseJHaem, Volume 6, Issue 2, April 2025.
Abstract In patients with X‐linked agammaglobulinemia (XLA), serum immunoglobulins are almost completely lacking. The prevalence of autoimmune diseases is low in XLA compared with other primary immunodeficiency diseases because antibodies are absent in XLA.
Takeaki Matsunaga   +6 more
wiley   +2 more sources

Clinical periodontal diagnosis

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi   +5 more
wiley   +1 more source

Burton's Agammaglobulinemia and COVID-19 [PDF]

open access: yesCureus, 2020
During the SARS-CoV-2 global pandemic, many patients who have co-morbid conditions are considered high risk for morbidity and mortality; however, those who are immunodeficient are at higher risk of becoming seriously ill. In this article, we present a 26-year old male with a history of X-linked agammaglobulinemia who presented to the hospital with ...
Justin G Hovey   +2 more
openaire   +4 more sources

Studies on Agammaglobulinemia VI. Hemostasis in Patients with Agammaglobulinemia.

open access: yesExperimental Biology and Medicine, 1956
Summary and Conclusions1. The activity or concentration of the clotting factors recognized at the present time have been determined in 7 patients with agammaglobulinemia. Four of the patients had the congenital-hereditary form of agammaglobulinemia and three had the acquired form of the disease. 2.
Robert A. Good, Paul G. Frick
openaire   +3 more sources

Bruton's agammaglobulinemia [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Probably slight; in a 1963 paper, two patients with lymphoma were reported and reference was made to two adults with hypoglobulinemia who also had lymphomas; recent surveys of XLA patients do not reveal any cases of lymphoma; however, long-term vigilance needs to be maintained; at least seven cases of adenocarcinoma of the gastrointestinal tract in ...
openaire   +2 more sources

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

open access: yesVIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma   +6 more
wiley   +1 more source

Use of Dynamic Contrast‐Enhanced Magnetic Resonance Imaging Combined With Serum Carcinoembryonic Antigen and Carbohydrate Antigen 19‐9 in Predicting Colorectal Cancer Liver Metastasis

open access: yesJournal of Clinical Ultrasound, Volume 53, Issue 4, Page 612-619, May 2025.
The study subjects were mainly CRC patients (n = 120), all of whom underwent the same comprehensive treatment regimen and were divided into the effective treatment group (n = 86) and the ineffective treatment group (n = 34) according to efficacy after treatment.
Hong‐Bo Ji   +4 more
wiley   +1 more source

Systematics, diagnosis and treatment of wound infections in chronic wounds: A position paper from WundDACH

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 5, Page 565-574, May 2025.
Summary Wound infections are still an interdisciplinary and interprofessional challenge, because of numerous complications, particularly in people with chronic wounds. There are many different concepts and approaches in this field today. Therefore, WundDACH, the umbrella organization of the German‐speaking wound healing societies, wrote a position ...
Joachim Dissemond   +12 more
wiley   +1 more source

Beyond TREC: Pivotal role of tandem TREC/KREC assay in Czech SCID NBS pilot programme

open access: yesPediatric Allergy and Immunology, Volume 36, Issue 5, May 2025.
Abstract Background Severe combined immunodeficiency (SCID) is a fatal but treatable inborn error of immunity (IEI). Newborn screening (NBS) using T‐cell receptor excision circles (TREC) has been adopted globally, with very few countries incorporating kappa recombination excision circles (KREC) to also detect early B‐cell development disorders, such as
Markéta Bloomfield   +23 more
wiley   +1 more source

X-linked agammaglobulinemia

open access: yesClinical Immunology and Immunopathology, 1991
X-linked agammaglobulinemia (XLA) patients manifest a very low production of immunoglobulins (Ig) of all classes and plasma cells are virtually absent. The XLA gene plays a crucial role in the transition of pre-B cells to later B cell stages, as hardly any slg-positive B lymphocytes can be detected.
R.K.B. Schuurman   +4 more
openaire   +3 more sources

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