Results 21 to 30 of about 155,399 (295)
Age-related macular degeneration [PDF]
The Lancet, 2008 Age-related macular degeneration is the leading cause of blindness in elderly populations of European descent. The most consistent risk factors associated with this ocular condition are increasing age and cigarette smoking. Genetic investigations have shown that complement factor H, a regulator of the alternative complement pathway, and LOC387715/HtrA1
Hanna R, Coleman +3 more
openaire +4 more sources
Morphometric analyses of the visual pathways in macular degeneration [PDF]
, 2014 Introduction. Macular degeneration (MD) causes central visual field loss. When field defects occur in both eyes and overlap, parts of the visual pathways are no longer stimulated.
Baseler, Heidi A. +8 more
core +6 more sources
PLoS ONE, 2021 ObjectiveThis study aimed to investigate the risk of Alzheimer's disease among patients with age-related macular degeneration and its association with confounding comorbidities.MethodThis was a population-based, retrospective cohort study.
Li-Yen Wen +9 more
doaj +1 more source
BMC Ophthalmology, 2023 Background The aim of this study was to describe features of disease activity in patients with treated stable macular neovascularisation (MNV) in neovascular age related macular degeneration (nAMD) using optical coherence tomography angiography (OCTA ...
Daren Hanumunthadu +6 more
doaj +1 more source
Innate immune biology in age-related macular degeneration
Frontiers in Cell and Developmental Biology, 2023 Age-related macular degeneration (AMD) is a neurodegenerative disease and a leading cause of irreversible vision loss in the developed world. While not classically described as an inflammatory disease, a growing body of evidence has implicated several ...
Karina Ascunce +4 more
doaj +1 more source
Interleukin-6 receptor blockade suppresses subretinal fibrosis in a mouse model [PDF]
International Journal of Ophthalmology, 2014 AIM:To determine the involvement of the interleukin (IL)-6 with the development of experimental subretinal fibrosis in a mouse model.METHODS:Subretinal fibrosis was induced by subretinal injection of macrophage-rich peritoneal exudate cells and the local
Wei Cui, Han Zhang, Zhe-Li Liu
doaj +1 more source
Neuroprotection for Age-Related Macular Degeneration
Ophthalmology Science, 2022 Age-related macular degeneration (AMD) is a leading cause of blindness worldwide. Early to intermediate AMD is characterized by the accumulation of lipid- and protein-rich drusen.
Jonathan B. Lin, MD, PhD +3 more
doaj +1 more source
Age-Related Macular or Retinal Degeneration?
Medicina, 2023 Age-related macular degeneration (AMD) is an eye disease that leads to progressive vision loss. Its prevalence has been increasing due to population aging.
Michalina Gałuszka +2 more
doaj +1 more source
Age-related macular degeneration: an overview
Revista Brasileira de Oftalmologia, 2021 Age-related macular degeneration is the most important cause of irreversible vision loss in the elderly and has been considered a severe public health problem. Current treatments have only been successful in delaying the loss of central vision.
Rogil José de Almeida Torres +1 more
doaj +1 more source
Complement C3 variant and the risk of age-related macular degeneration [PDF]
, 2007 Background: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors.
Armbrecht, AM +16 more
core +1 more source