Results 61 to 70 of about 156,095 (237)

Age-related macular degeneration

open access: yesSurvey of Ophthalmology, 1988
Age-related macular degeneration (AMD) is the leading cause of irreversible severe visual loss in the United States in people over 50 years of age. The nonexudative stage includes hard drusen (associated with localized dysfunction of the retinal pigment epithelium [RPE]), soft drusen (associated with diffuse dysfunction of the RPE), and geographic ...
N M, Bressler, S B, Bressler, S L, Fine
openaire   +2 more sources

Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review. [PDF]

open access: yes, 2019
As a part of the central nervous system, the retina may reflect both physiologic processes and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put forth to understand how Alzheimer's disease (AD) pathology may manifest
Honma, Patrick   +2 more
core   +1 more source

Age- and sex-based evaluation of the association between refractive error and age-related macular degeneration in the Korean population.

open access: yesPLoS ONE, 2020
PURPOSE:The aim of this study was to investigate the association between refractive error and prevalence of age-related macular degeneration (AMD) in Korean adults, based on the sex and age group.
Kook Lee   +4 more
doaj   +1 more source

Distinguishing wet from dry age-related macular degeneration using three-dimensional computer-automated threshold Amsler grid testing [PDF]

open access: yes, 2011
Background/aims: With the increased efficacy of current therapy for wet age-related macular degeneration (AMD), better ways to detect wet AMD are needed.
Bababeygy, Simon R.   +5 more
core   +1 more source

Age-related macular degeneration: current treatments

open access: yesClinical Ophthalmology, 2009
Jean Pierre Hubschman, Shantan Reddy, Steven D SchwartzJules Stein Eye Institute, Department of Ophthalmology, University of California, David Geffen School of Medicine, Los Angeles, California, USAPurpose: Although important progress has been made in ...
Jean Pierre Hubschman   +2 more
doaj  

A variance components factor model for genetic association studies: a Bayesian analysis.

open access: yes, 2010
Studies of gene-trait associations for complex diseases often involve multiple traits that may vary by genotype groups or patterns. Such traits are usually manifestations of lower-dimensional latent factors or disease syndromes.
Nonyane, BAS, Whittaker, JC
core   +1 more source

The efficacy of ranibizumab treatment in clinical practice in patients with the wet form of age-related macular degeneration. The results of the Czech National Registry

open access: yesBiomedical Papers, 2015
Aims: The aim of this communication was to evaluate ranibizumab in the treatment of wet age-related macular degeneration. Methods: Anonymised data on treatment efficacy and safety were consecutively entered into the Czech national database.
Oldrich Chrapek   +8 more
doaj   +1 more source

Interleukin-13 and age-related macular degeneration [PDF]

open access: yesInternational Journal of Ophthalmology, 2017
AIM: To identify the effects of interleukin (IL)-13 on retinal pigment epithelial (RPE) cells and the IL-13 level in aqueous humor of age-related macular degeneration (AMD) patients.
Bo Fu, Zhe-Li Liu, Han Zhang, Feng Gu
doaj   +1 more source

Macular pigment and age related macular degeneration [PDF]

open access: yesBritish Journal of Ophthalmology, 1999
The yellow coloration of the macula lutea is attributable to the presence of macular pigment in the axons of its photoreceptors.1 In the 1980s several investigators demonstrated that macular pigment consists of the xanthophyll isomers, lutein and zeaxanthin.2 3 Although the role of the macular pigment remains uncertain, several functions have been ...
Beatty, S.   +4 more
openaire   +3 more sources

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