Fibulin-5 mutations link inherited neuropathies, age-related macular degeneration and hyperelastic skin [PDF]
To identify the disease-causing gene responsible for an autosomal dominantly inherited Charcot-Marie-Tooth neuropathy subtype in a family excluded for mutations in the common Charcot-Marie-Tooth genes, we used array-based sequence capture to ...
Auer-Grumbach, Michaela +16 more
core
Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage. [PDF]
Age-related macular degeneration (AMD) ranks third among the leading causes of visual impairment with a blindness prevalence rate of 8.7%. Despite several treatment regimens, such as anti-angiogenic drugs, laser therapy, and vitamin supplementation ...
Chwa, Marilyn +6 more
core +1 more source
Micronutrients in Age-Related Macular Degeneration [PDF]
Several lines of evidence from in vitro and in vivo studies suggest that specific micronutrients may have beneficial effects in age-related macular degeneration (AMD). Such effects appear to be complex and may include filtering short wavelength light and attenuating oxidative and inflammatory damage as well as other structural and physiological factors.
Aslam, Tariq +6 more
openaire +3 more sources
Learn Single-horizon Disease Evolution for Predictive Generation of Post-therapeutic Neovascular Age-related Macular Degeneration [PDF]
Yuhan Zhang +4 more
openalex +1 more source
Association of drusen deposition with choroidal intercapillary pillars in the aging human eye [PDF]
PURPOSE. To determine the pattern of drusen accumulation with age and to investigate the initial sites of deposition and their relationship to choroidal capillaries in human donor eyes from the eye bank of Moorfields Eye Hospital.METHODS.
Al Hosaini, H +5 more
core +1 more source
Intraocular lenses in age-related macular degeneration [PDF]
Purpose: The aim of this work is to review the lenses, assessing their advantages and disadvantages. We describe a total of seven types of intraocular lenses (IOLs) recommended for age-related macular degeneration (AMD).
A Agarwal +30 more
core +1 more source
The role and therapeutic potential of melatonin in age-related ocular diseases [PDF]
The eye is continuously exposed to solar UV radiation and pollutants, making it prone to oxidative attacks. In fact, oxidative damage is a major cause of age-related ocular diseases including cataract, glaucoma, age-related macular degeneration and ...
Colligris, Basilio +3 more
core +2 more sources
Choriocapillaris in Age-Related Macular Degeneration
Age-related macular degeneration (AMD) is a multifactorial disease characterized by progressive alterations of different retinal structures ultimately leading to vision loss.
Giovanni Neri +6 more
doaj +1 more source
Blindness incidence in Germany - A population-based study from Württemberg-Hohenzollern [PDF]
Few data on the incidence of blindness in Germany are available. We analysed causes of legal blindness for the region Württemberg-Hohenzollern (population 5.5 million) in order to help fill in this gap.
Klauss, V. +4 more
core +1 more source

