Results 141 to 150 of about 629,919 (312)
Age Concern's response to the Government's consultation 'Equality and diversity: the way ahead'
, 2003 SIGLEAvailable from British Library Document Supply Centre- DSC:m03/20787 / BLDSC - British Library Document Supply CentreGBUnited ...
Age Concern England (United Kingdom)
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Diversity at Mason: The Pursuit of Transformative Education
, 2011 The Diversity at Mason series has been produced by the university's Diversity Research Group, which consists of an interdisciplinary group of faculty, administrators, and students who have been meeting once a semester since Spring 2004.
Haan, Jennifer +5 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Age Discrimination and Diversity
, 2011 This volume of essays is concerned with the discrimination against older people that results from a failure to recognise their diversity. By considering the unique combinations of discrimination that arise from the interrelationship of age and gender, pensions, ethnicity, sexual orientation, socio-economic class and disability, the contributors ...
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Towards a fuller, more nuanced narrative of Chalcolithic and Early Bronze Age Britain 2500-1500 BC
, 2008 This contribution considers some of the many recent advances in our understanding of Chalcolithic and Bronze Age Britain and uses these to highlight the weak points in our current state of knowledge.
Sheridan, J A, Sheridan, Alison
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Age-Diversity-Management in Teams und Organisationen
, 2016 Aufgrund gesamtgesellschaftlicher Veränderungen ist für viele Unternehmen eine altersdiverse Belegschaft längst Realität. Vor diesem Hintergrund und der Aussicht, dass die Altersdiversität der Belegschaft in den meisten Unternehmen in Zukunft noch weiter
Florian Kunze +3 more
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source