Results 91 to 100 of about 2,022,626 (303)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Agricultural data prediction by means of neural network
Agricultural Economics (AGRICECON), 2011 The contribution deals with the prediction of crop yield levels, using an artificial intelligence approach, namely a multi-layer neural network model.
Jiří ŠŤASTNÝ +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Predicting the risk for progression of acquired myopia in school-age children
Journal of Ophthalmology, 2018 Background: Prediction of myopia progression in children is of practical relevance. Purpose: To develop a prediction table for comprehensive assessment of the risks for progression of acquired myopia in school-age children.
T.E. Tsybulska +2 more
doaj +1 more source
Comparison of Raw Acceleration from the GENEA and ActiGraph™ GT3X+ Activity Monitors [PDF]
, 2013 Purpose: To compare raw acceleration output of the ActiGraph™ GT3X+ and GENEA activity monitors. Methods: A GT3X+ and GENEA were oscillated in an orbital shaker at frequencies ranging from 0.7 to 4.0 Hz (ten 2-min trials/frequency) on a fixed radius of 5.
Dinesh John +15 more
core +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Bayesian Age-Period-Cohort Modeling and Prediction - BAMP [PDF]
The software package BAMP provides a method of analyzing incidence or mortality data on the Lexis diagram, using a Bayesian version of an age-period-cohort model. A hierarchical model is assumed with a binomial model in the first-stage.
Leonhard Held, Volker J. Schmid
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Co‐DeepNet: A Cooperative Convolutional Neural Network for DNA Methylation‐Based Age Prediction
CAAI Transactions on Intelligence TechnologyPrediction of the age of each individual is possible using the changing pattern of DNA methylation with age. In this paper an age prediction approach to work out multivariate regression problems using DNA methylation data is developed.
Najmeh Sadat Jaddi +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source