Results 131 to 140 of about 2,462,697 (323)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Age-realted dementia in Kazahstan: adaptation of the 10/66 dementia research group population -based study protocol [PDF]

, 2014
Background. The prevalence of dementia is increasing worldwide as the population ages and affects 10 % of the population over 65 years old and 40 % of people over the age of 80.[1] In Kazakhstan, as well as in other countries around the world, the ...
Adambekov, Sh., Alimbetov, D., Askarova, Sholpan, Kaiyrlykyzy, A.   +3 more
core  

Geographical distribution of centenarians in Colombia: an analysis of three databases

Revista de la Facultad de Medicina, 2017
Introduction: Individuals aged one hundred years or more are of interest for the study of the aging process, which has been scarcely addressed in Colombia.
Diego Rosselli, Daniela Yucumá, María José Polanía, Jenny Carolina Machado   +3 more
doaj   +1 more source

Quality of life and socio-demographic factors associated with nutritional risk in Brazilian community-dwelling individuals aged 80 and over: cluster analysis and ensemble methods. [PDF]

Front Nutr, 2023
Brech GC, da Silva VC, Alonso AC, Machado-Lima A, da Silva DF, Micillo GP, Bastos MF, de Aquino RC.   +7 more
europepmc   +1 more source

Outcomes of lumbar spinal fusion in super-elderly patients aged 80 years and over: Comparison with patients aged 65 years and over, and under 80 years

Brain and Spine, 2021
Haewon Jeong, Hee-Jung Son, Y. Jo, H. Ahn, Jooyoung You, Sang Hoon Park, Chang-Nam Kang   +6 more
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Indigenous child safety [PDF]

Indigenous children are over represented in areas where child safety and security are compromised, argues this report. Summary National data show that Aboriginal and Torres Strait Islander children are over-represented in various aspects of child ...

core  

Discovery of a New Supernova Remnant in the Direction of G69.7+1.0 [PDF]

, 2000
We discovered a middle-aged supernova remnant (SNR) in the vicinity of G69.7+1.0 using the ASCA satellite. G69.7+1.0 was identified in the 2.7 GHz survey and classified as a shell-type SNR with a diameter of 16 arcmin.
Miyata, Emi, Tsunemi, Hiroshi, Yoshita, Kumi   +2 more
core   +3 more sources

Comparison of Radical Cystectomy with Conservative Treatment in Geriatric ( 80) Patients with Muscle-Invasive Bladder Cancer

International Brazilian Journal of Urology, 2013
Introduction The aim of this study was to compare overall survival in elderly patients (≥ 80 years) with muscle-invasive bladder cancer (MIBC) undergoing either radical cystectomy (RC) or conservative treatment.
Thomas Martini, Roman Mayr, Clemens Wehrberger, Christopher Dechet, Michele Lodde, Salvatore Palermo, Emanuela Trenti, Evi Comploj, Armin Pycha   +8 more
doaj   +1 more source