Results 121 to 130 of about 474,048 (356)

Telomere dysfunction in ageing and age-related diseases

Nature Cell Biology, 2022
F. Rossiello, D. Jurk, J. Passos, F. d’Adda di Fagagna   +3 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Physical Activity Among Iranian Former Sportsmen and Athletes as Possible Evidence for Continuity Theory of Aging

Iranian Rehabilitation Journal, 2019
Objectives: Physical activity in late life may be a continuity of activity pattern in the early stages of life. The current study aimed to assess physical activity levels in former Iranian sportsmen and athletes, in 2016.
Salman Naderyan, Robab Sahaf, Ahmad Ali Akbari Kamrani, Yadollah Abolfathi Momtaz, Hossein Ghasemzadeh, Shahab Papi   +5 more
doaj  

A longitudinal cohort study on dispensed analgesic and psychotropic medications in older adults before, during, and after the COVID-19 pandemic: the HUNT study

BMC Geriatrics
Background There is a growing concern and debate over the inappropriate use of analgesics and psychotropic medications by older adults, especially those with dementia.
Tanja Louise Ibsen, Ekaterina Zotcheva, Sverre Bergh, Debby Gerritsen, Gill Livingston, Hilde Lurås, Svenn-Erik Mamelund, Anne Marie Mork Rokstad, Bjørn Heine Strand, Richard C. Oude Voshaar, Geir Selbæk   +10 more
doaj   +1 more source

Study on thermal cycling ageing resistance of performances of polypropylene/elastomer/boron nitride nanocomposites for high voltage direct current cable insulation [PDF]

Jing Li, Yu Gao, Zheng Song, Baixin Liu, Chenyi Guo, Yu Chen, Junguo Gao, Boxue Du   +7 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Cohort Profile: The Amirkola Health and Ageing Project (AHAP) [PDF]

, 2013
Seyed Reza Hosseini, Robert G. Cumming, Farzan Kheirkhah, Hajighorban Nooreddini, Mohammadali Baiani, Ebrahim Mikaniki, Mohammad Taghipour‐Darzi, Haleh Akhavan‐Niaki, Seyed Ahmad Rasolinejad, Amrollah Mostafazadeh, Hadi Parsian, Ali Bijani   +11 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

The World Health Organization (WHO) approach to healthy ageing

Maturitas, 2020
E. Rudnicka, Paulina Napierała, A. Podfigurna, B. Męczekalski, R. Smolarczyk, M. Grymowicz   +5 more
semanticscholar   +1 more source

DEMOGRAPHIC SHIFT, POPULATION AGEING AND ECONOMIC GROWTH IN CHINA: A COMPUTABLE GENERAL EQUILIBRIUM ANALYSIS [PDF]

, 2008
Xiujian Peng
openalex   +1 more source