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Seductive Solutions, Inspiration, Easy-to-Remember Phrases, and Ambiguity: Why Is the Idea of Active Ageing so Successful? [PDF]
The idea of active ageing has become one of the most influential perspectives in modern gerontology, social work, and social policy. This paper discusses factors that helped to establish active ageing as a successful theoretical concept that has ...
Hasmanová Marhánková, Jaroslava
core +3 more sources
According to the antagonistic pleiotropy theory of ageing, natural selection has favoured genes conferring short-term benefits to the organism at the cost of deterioration in later life. The 'disposable soma' theory expresses this as a life-history strategy in which somatic maintenance is below the level required to prevent ageing, thus enabling higher
Robert M. Seymour, Peter D. Sozou
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Background Application of objective measurement of stroke gait with accelerometer-based wearable technology and associated algorithms is increasing, despite reports questioning the accuracy of this technique in quantifying specific stroke-related gait ...
Sarah A. Moore+5 more
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The future of Age and Ageing [PDF]
The delivery of healthcare in the United Kingdom is going through a period of change, with many new developments. Some of these represent the aspirations of politicians and those who manage the National Health Service, and others are being forced upon us because of the shortage of resources (not always financial).
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Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity
G4C2 hexanucleotide repeat expansions in a non-coding region of the C9orf72 gene are the most common cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Javier Morón-Oset+9 more
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Dynamical network stability analysis of multiple biological ages provides a framework for understanding the aging process [PDF]
Widespread interest in non-destructive biomarkers of aging has led to a curse of plenty: a multitude of biological ages that each proffers a 'true' health-adjusted age of an individual. While each measure provides salient information on the aging process, they are each univariate, in contrast to the "hallmark" and "pillar" theories of aging which are ...
arxiv +1 more source
HAGR: the Human Ageing Genomic Resources [PDF]
The Human Ageing Genomic Resources (HAGR) is a collection of online resources for studying the biology of human ageing. HAGR features two main databases: GenAge and AnAge. GenAge is a curated database of genes related to human ageing.
Costa, Joana+2 more
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Ageing and vascular ageing [PDF]
Abstract There is an age related decline in various physiological processes. Vascular ageing is associated with changes in the mechanical and the structural properties of the vascular wall, which leads to the loss of arterial elasticity and reduced arterial compliance.
B Jani, C Rajkumar
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[This corrects the article DOI: 10.1371/journal.pone.0161705.].
Cognitive Function and Ageing Studies (DFAS)
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A multidimensional systems biology analysis of cellular senescence in aging and disease
Background Cellular senescence, a permanent state of replicative arrest in otherwise proliferating cells, is a hallmark of aging and has been linked to aging-related diseases.
Roberto A. Avelar+15 more
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