Results 11 to 20 of about 998,871 (360)

The use of urinary proteomics in the assessment of suitability of mouse models for ageing [PDF]

open access: yes, 2017
Ageing is a complex process characterised by a systemic and progressive deterioration of biological functions. As ageing is associated with an increased prevalence of age-related chronic disorders, understanding its underlying molecular mechanisms can ...
Bajwa, Seerat   +17 more
core   +3 more sources

Comprehensive measurement of stroke gait characteristics with a single accelerometer in the laboratory and community: a feasibility, validity and reliability study

open access: yesJournal of NeuroEngineering and Rehabilitation, 2017
Background Application of objective measurement of stroke gait with accelerometer-based wearable technology and associated algorithms is increasing, despite reports questioning the accuracy of this technique in quantifying specific stroke-related gait ...
Sarah A. Moore   +5 more
doaj   +1 more source

Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity

open access: yesActa Neuropathologica Communications, 2023
G4C2 hexanucleotide repeat expansions in a non-coding region of the C9orf72 gene are the most common cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Javier Morón-Oset   +9 more
doaj   +1 more source

Balancing the struggle to live with dementia: a systematic meta-synthesis of coping

open access: yesBMC Geriatrics, 2019
Background People with dementia describe experiences of loss that threaten their autonomy and ability to contribute to society. They often have difficulties with orientation, loss of roll function, and fear about the future, and need help from others. An
Guro Hanevold Bjørkløf   +5 more
doaj   +1 more source

A Comparative Study on the Influence of DC/DC-Converter Induced High Frequency Current Ripple on Lithium-Ion Batteries [PDF]

open access: yes, 2019
Modern battery energy systems are key enablers of the conversion of our energy and mobility sector towards renewability. Most of the time, their batteries are connected to power electronics that induce high frequency current ripple on the batteries that ...
Korth Pereira Ferraz, Pablo   +1 more
core   +1 more source

Feedback between p21 and reactive oxygen production is necessary for cell senescence

open access: yesMolecular Systems Biology, 2010
Cellular senescence—the permanent arrest of cycling in normally proliferating cells such as fibroblasts—contributes both to age‐related loss of mammalian tissue homeostasis and acts as a tumour suppressor mechanism.
João F Passos   +13 more
doaj   +1 more source

A multidimensional systems biology analysis of cellular senescence in aging and disease

open access: yesGenome Biology, 2020
Background Cellular senescence, a permanent state of replicative arrest in otherwise proliferating cells, is a hallmark of aging and has been linked to aging-related diseases.
Roberto A. Avelar   +15 more
doaj   +1 more source

Youth Unemployment, Ageing and Regional Welfare: The Regional Labour Market Policy Response to Ageing in Sweden [PDF]

open access: yes, 2012
The aim of this paper is to discuss the regional labour market policy response to demographic ageing in Sweden and its consequences on the labour supply of young adults.
Kahila, Petri, Rauhut, Daniel
core   +1 more source

The ENJOY MAP for HEALTH: Exercise interveNtion outdoor proJect in the cOmmunitY for older people—More Active People for HEALTHier communities: a study protocol

open access: yesBMC Public Health, 2022
Background Physical activity is important to maintain health in older age, with physical activity in the outdoors providing mental and physical health benefits for all age groups.
Pazit Levinger   +7 more
doaj   +1 more source

The Expression and Function of Metastases Associated Lung Adenocarcinoma Transcript-1 Long Non-Coding RNA in Subchondral Bone and Osteoblasts from Patients with Osteoarthritis

open access: yesCells, 2021
Metastasis Associated Lung Adenocarcinoma Transcript-1 (MALAT1) is implicated in regulating the inflammatory response and in the pathology of several chronic inflammatory diseases, including osteoarthritis (OA).
Fawzeyah A. Alnajjar   +7 more
doaj   +1 more source

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