Results 11 to 20 of about 723,040 (308)

Challenging ageism: A guide to talking about ageing and older age [PDF]

, 2021
This guide from UK-based Centre for Ageing Better is designed as a practical tool to support organisations in communicating about aging and older age.Ageism is widespread in society and can be found everywhere from our workplaces and health systems to ...
Centre for Ageing Better
core   +2 more sources

Promoting Independence Through quality dementia Care at Home (PITCH): a research protocol for a stepped-wedge cluster-randomised controlled trial

Trials, 2021
Background Home care service providers are increasingly supporting clients living with dementia. Targeted and comprehensive dementia-specific training for home care staff is necessary to meet this need. This study evaluates a training programme delivered
Steven Savvas, Anita M. Y. Goh, Frances Batchelor, Colleen Doyle, Erica Wise, Esther Tan, Anita Panayiotou, Sue Malta, Margaret Winbolt, Phillip Clarke, Jason Burton, Lee-Fay Low, Samantha M. Loi, Anne Fairhall, Meg Polacsek, Jay Stiles, Fenny Muliadi, Nadia Chau, Samuel Scherer, David Ames, Tanara Vieira Sousa, Briony Dow   +21 more
doaj   +1 more source

A landscape assessment of the use of patient reported outcome measures in research, quality improvement and clinical care across a healthcare organisation

BMC Health Services Research, 2023
Background Patient reported outcome measures (PROMs) can be used by healthcare organisations to inform improvements in service delivery. However, routine collection of PROMs is difficult to achieve across an entire healthcare organisation.
David A. Snowdon, Velandai Srikanth, Richard Beare, Lucy Marsh, Emily Parker, Kim Naude, Nadine E. Andrew   +6 more
doaj   +1 more source

Establishing an ethics and governance framework for access to and linkage of electronic health data for research projects.

International Journal of Population Data Science, 2022
Objectives To develop an ethics and governance framework for the National Centre for Healthy Ageing (NCHA) data platform that supports: streamlined access to data for research; transfer of data into secure data environments; linkage with a range of ...
Emily Parker, Tanya Ravipati, Richard Beare, Velandai Srikanth, Nadine Andrew   +4 more
doaj   +1 more source

mTOR at the nexus of nutrition, growth, ageing and disease

Nature reviews. Molecular cell biology, 2020
The mTOR pathway integrates a diverse set of environmental cues, such as growth factor signals and nutritional status, to direct eukaryotic cell growth. Over the past two and a half decades, mapping of the mTOR signalling landscape has revealed that mTOR
Grace Y. Liu, D. Sabatini
semanticscholar   +1 more source

Aging is associated with increased chromatin accessibility and reduced polymerase pausing in liver

Molecular Systems Biology, 2022
Regulation of gene expression is linked to the organization of the genome. With age, chromatin alterations occur on all levels of genome organization, accompanied by changes in the gene expression profile.
Mihaela Bozukova, Chrysa Nikopoulou, Niklas Kleinenkuhnen, Dora Grbavac, Katrin Goetsch, Peter Tessarz   +5 more
doaj   +1 more source

Who is your community? Co-designing a community engagement strategy for an emerging data platform.

International Journal of Population Data Science, 2022
Objectives To co-design with older Australian consumers and stakeholders a strategy for engaging the wider community with an emerging data platform, involving linked routinely collected electronic health data for research.
Kim Naude, Emily Parker, Roisin McNaney, Michelle Daniel, Richard Beare, Velandai Srikanth, Nadine Andrew   +6 more
doaj   +1 more source

cGAS–STING drives ageing-related inflammation and neurodegeneration

Nature, 2023
The cGAS–STING signalling pathway is a critical driver of chronic inflammation and functional decline during ageing, and could be targeted to halt neurodegenerative processes during old age.
M. F. Gulen, Natasha Samson, Alexander Keller, Marius Schwabenland, Chong Liu, Selene Glück, Vivek V. Thacker, L. Favre, Bastien Mangeat, Lona J Kroese, P. Krimpenfort, M. Prinz, A. Ablasser   +12 more
semanticscholar   +1 more source

Ageing and Covid-19

, 2021
This volume presents a range of research approaches to the exploration of ageing during a pandemic situation. One of the first collections of its kind, it offers an array of studies employing research methodologies that lend themselves to replication in ...

core   +1 more source

Implementing care for healthy ageing

BMJ Global Health, 2022
The WHO concept of Healthy Ageing (ie, the process of developing and maintaining the functional ability that enables well-being in older age) has initiated a global discussion about the need for shifting paradigms to reorient health and social services ...
Anshu Banerjee, Yuka Sumi, Matteo Cesari, Andrew Briggs, Hyobum Jang, Ritu Sadana, Jotheeswaran Amuthavalli Thiyagarajan, Zee A Han, Monica Perracini   +8 more
doaj   +1 more source