Heatwaves, ageing, and dementia: assessing mortality risks and adaptation strategies in a warming China. [PDF]
Fu X, Huang S.
europepmc +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Effect of Collar Diameter and Simulated Aging on the Orthogonal Load Resistance of Orthodontic Miniscrews. [PDF]
Sfondrini MF +7 more
europepmc +1 more source
The Effect of DC Electro-thermal Ageing on Electrical Treeing in Polyethylene
Adrian Mantsch +3 more
openalex +2 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Correction to: Validation of the 4AT for assessing recovery from delirium in older hospital patients. [PDF]
europepmc +1 more source
Thermo-Oxidative Decomposition and Ageing of Polymer/POSS Hybrids and Nanocomposites-Failure Predictions and Lifetime Design for Circular End-of-Life Planning. [PDF]
Majka TM +3 more
europepmc +1 more source
Envejecimiento activo y participación política / Active ageing and political participation
Imanol Zubero Beaskoetxea
openalex +2 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source

