Results 21 to 30 of about 929,250 (364)
Geriatricians' views of advance decisions and their use in clinical care in England: qualitative study [PDF]
Background: an anticipatory decision document records a person's wishes regarding medical treatment at a time when they have capacity to make choices, to be enacted when this capacity is lost. In England and Wales an advance decision to refuse treatment (
Bond, Catherine Jane, Lowton, Karen
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Balancing the struggle to live with dementia: a systematic meta-synthesis of coping
Background People with dementia describe experiences of loss that threaten their autonomy and ability to contribute to society. They often have difficulties with orientation, loss of roll function, and fear about the future, and need help from others. An
Guro Hanevold Bjørkløf+5 more
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Metastasis Associated Lung Adenocarcinoma Transcript-1 (MALAT1) is implicated in regulating the inflammatory response and in the pathology of several chronic inflammatory diseases, including osteoarthritis (OA).
Fawzeyah A. Alnajjar+7 more
doaj +1 more source
Feedback between p21 and reactive oxygen production is necessary for cell senescence
Cellular senescence—the permanent arrest of cycling in normally proliferating cells such as fibroblasts—contributes both to age‐related loss of mammalian tissue homeostasis and acts as a tumour suppressor mechanism.
João F Passos+13 more
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Background Physical activity is important to maintain health in older age, with physical activity in the outdoors providing mental and physical health benefits for all age groups.
Pazit Levinger+7 more
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The longitudinal progression of autonomic dysfunction in Parkinson's disease: A 7-year study
BackgroundAutonomic dysfunction, including gastrointestinal, cardiovascular, and urinary dysfunction, is often present in early Parkinson's Disease (PD). However, the knowledge of the longitudinal progression of these symptoms, and the connection between
Charlotte B. Stewart+9 more
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Older care-home residents as collaborators or advisors in research: a systematic review [PDF]
Background: patient and public involvement (PPI) in research can enhance its relevance. Older care-home residents are often not involved in research processes even when studies are care-home focused.
Andrea Kenkmann+10 more
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The use of urinary proteomics in the assessment of suitability of mouse models for ageing [PDF]
Ageing is a complex process characterised by a systemic and progressive deterioration of biological functions. As ageing is associated with an increased prevalence of age-related chronic disorders, understanding its underlying molecular mechanisms can ...
Bajwa, Seerat+17 more
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PFA-GAN: Progressive Face Aging with Generative Adversarial Network [PDF]
Face aging is to render a given face to predict its future appearance, which plays an important role in the information forensics and security field as the appearance of the face typically varies with age. Although impressive results have been achieved with conditional generative adversarial networks (cGANs), the existing cGANs-based methods typically ...
arxiv +1 more source
Vascular biology of ageing—implications in hypertension [PDF]
Ageing is associated with functional, structural and mechanical changes in arteries that closely resemble the vascular alterations in hypertension. Characteristic features of large and small arteries that occur with ageing and during the development of ...
Harvey, Adam+2 more
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