Results 21 to 30 of about 929,250 (364)

Geriatricians' views of advance decisions and their use in clinical care in England: qualitative study [PDF]

open access: yes, 2011
Background: an anticipatory decision document records a person's wishes regarding medical treatment at a time when they have capacity to make choices, to be enacted when this capacity is lost. In England and Wales an advance decision to refuse treatment (
Bond, Catherine Jane, Lowton, Karen
core   +1 more source

Balancing the struggle to live with dementia: a systematic meta-synthesis of coping

open access: yesBMC Geriatrics, 2019
Background People with dementia describe experiences of loss that threaten their autonomy and ability to contribute to society. They often have difficulties with orientation, loss of roll function, and fear about the future, and need help from others. An
Guro Hanevold Bjørkløf   +5 more
doaj   +1 more source

The Expression and Function of Metastases Associated Lung Adenocarcinoma Transcript-1 Long Non-Coding RNA in Subchondral Bone and Osteoblasts from Patients with Osteoarthritis

open access: yesCells, 2021
Metastasis Associated Lung Adenocarcinoma Transcript-1 (MALAT1) is implicated in regulating the inflammatory response and in the pathology of several chronic inflammatory diseases, including osteoarthritis (OA).
Fawzeyah A. Alnajjar   +7 more
doaj   +1 more source

Feedback between p21 and reactive oxygen production is necessary for cell senescence

open access: yesMolecular Systems Biology, 2010
Cellular senescence—the permanent arrest of cycling in normally proliferating cells such as fibroblasts—contributes both to age‐related loss of mammalian tissue homeostasis and acts as a tumour suppressor mechanism.
João F Passos   +13 more
doaj   +1 more source

The ENJOY MAP for HEALTH: Exercise interveNtion outdoor proJect in the cOmmunitY for older people—More Active People for HEALTHier communities: a study protocol

open access: yesBMC Public Health, 2022
Background Physical activity is important to maintain health in older age, with physical activity in the outdoors providing mental and physical health benefits for all age groups.
Pazit Levinger   +7 more
doaj   +1 more source

The longitudinal progression of autonomic dysfunction in Parkinson's disease: A 7-year study

open access: yesFrontiers in Neurology, 2023
BackgroundAutonomic dysfunction, including gastrointestinal, cardiovascular, and urinary dysfunction, is often present in early Parkinson's Disease (PD). However, the knowledge of the longitudinal progression of these symptoms, and the connection between
Charlotte B. Stewart   +9 more
doaj   +1 more source

Older care-home residents as collaborators or advisors in research: a systematic review [PDF]

open access: yes, 2016
Background: patient and public involvement (PPI) in research can enhance its relevance. Older care-home residents are often not involved in research processes even when studies are care-home focused.
Andrea Kenkmann   +10 more
core   +1 more source

The use of urinary proteomics in the assessment of suitability of mouse models for ageing [PDF]

open access: yes, 2017
Ageing is a complex process characterised by a systemic and progressive deterioration of biological functions. As ageing is associated with an increased prevalence of age-related chronic disorders, understanding its underlying molecular mechanisms can ...
Bajwa, Seerat   +17 more
core   +3 more sources

PFA-GAN: Progressive Face Aging with Generative Adversarial Network [PDF]

open access: yesIEEE Transactions on Information Forensics and Security, 2021, 2020
Face aging is to render a given face to predict its future appearance, which plays an important role in the information forensics and security field as the appearance of the face typically varies with age. Although impressive results have been achieved with conditional generative adversarial networks (cGANs), the existing cGANs-based methods typically ...
arxiv   +1 more source

Vascular biology of ageing—implications in hypertension [PDF]

open access: yes, 2015
Ageing is associated with functional, structural and mechanical changes in arteries that closely resemble the vascular alterations in hypertension. Characteristic features of large and small arteries that occur with ageing and during the development of ...
Harvey, Adam   +2 more
core   +1 more source

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