Results 41 to 50 of about 998,871 (360)
Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals
Nature Communications, 2016 Removal of the C. elegans germline substantially increases organismal lifespan. Here, Nakamura et al. show that the transcription factors MML-1 and MXL-2 coordinate this process in that they reduce TOR signalling and increase autophagy by regulating ...
Shuhei Nakamura +9 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij +11 more
wiley +1 more source
Ageing in Action: Hollywood’s Ageing Ensemble Action Hero Series [PDF]
, 2017 This paper explores the treatment of ageing in the ensemble action hero series RED (2010 and 2013) starring Bruce Willis and Helen Mirren and The Expendables (2010, 2012, and 2014) starring Sylvester Stallone and other 1980s action stars.
Gates, Philippa
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Chemotherapy‐induced peripheral neuropathy remains a major complication in pediatric cancer, with disrupted somatosensory and nociceptive processing being a key aspect. This review synthesizes empirical studies on alterations in somatosensory and nociceptive processing in children and adolescents with cancer.
Julia Schweiger +4 more
wiley +1 more source
, 2018 This chapter reviews studies that have examined age-related anatomic and functional changes in sensory, neuromuscular, and cognitive systems that impair the control of balance and gait. Specifically, we examine age-related changes in peripheral systems: lower-limb sensation, visual functions such as contrast sensitivity and depth perception, vestibular
Lord, SR, Delbaere, K, Sturnieks, DL
openaire +3 more sources
Healthy ageing: ageing safely [PDF]
European Heart Journal Supplements, 2001 The population of the developed world is steadily ageing. In the European Union, approximately 22% of persons are over 60 years of age and this is projected to increase to more than 27% by the year 2020. This has major implications for health care resources and the productive workforce. Ageing is accompanied by a decline in the physiological reserve of
openaire +2 more sources
Phenomenology of ageing in the Kardar-Parisi-Zhang equation
, 2012 We study ageing during surface growth processes described by the one-dimensional Kardar-Parisi-Zhang equation. Starting from a flat initial state, the systems undergo simple ageing in both correlators and linear responses and its dynamical scaling is ...
A. L. Barabási +6 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele +19 more
wiley +1 more source
Results of the Childhood Cancer and Leukaemia Group's United Kingdom Relapsed Wilms Tumour Trial
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The United Kingdom relapsed Wilms tumour (UKW‐R) trial aimed to improve the historically low survival rates after relapse of Wilms tumour (WT) through a prospective national risk‐stratified protocol. The trial also evaluated efficacy and toxicity of high‐dose melphalan.
Sucheta J. Vaidya +10 more
wiley +1 more source
The Relationship Between Personality Traits of Older Adults and Elder Abuse
Sālmand, 2023 Objectives This study aims to investigate the relationship between the big-five personality traits (extroversion, neuroticism, agreeableness, conscientiousness, and openness to experience) and elder abuse.
Mina Rahimzade Sani +3 more
doaj