Results 71 to 80 of about 688,654 (273)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Infectious Disease ModellingThis paper presents a comprehensive agent-based model for the spread of an infection in a network of cities. Directional mobility is defined between each two cities and can take different values.
Leen Alrawas +2 more
doaj +1 more source
Designing community care systems with AUML [PDF]
, 2003 This paper describes an approach to developing an appropriate agent environment appropriate for use in community care applications. Key to its success is that software designers collaborate with environment builders to provide the levels of cooperation ...
Beer, M., Hill, R., Huang, W.
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The ABM Template Models -- A Reformulation with Reference Implementations [PDF]
This paper refines a well-known set of template models for agent-based modeling and offers new reference implementations. It also addresses issues of design, flexibility, and ease of use that are relevant to the choice of an agent-based modeling platform.
Alan G. Isaac
core
NL4Py: Agent-Based Modeling in Python with Parallelizable NetLogo Workspaces
, 2018 NL4Py is a NetLogo controller software for Python, for the rapid, parallel execution of NetLogo models. NL4Py provides both headless (no graphical user interface) and GUI NetLogo workspace control through Python. Spurred on by the increasing availability
Garibay, Ivan, Gunaratne, Chathika
core +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
The Unrecognized Death Toll of COVID-19 in the United States
The Lancet Regional Health. Americas, 2021 Seyed M. Moghadas, Alison P. Galvani
doaj +1 more source
Pedestrian Attribute Analysis Using Agent-Based Modeling
Applied Sciences, 2020 Crossing a road outside of a crosswalk is a major cause of pedestrian fatalities. The aim of this study was to investigate this type of behavior for different pedestrian attributes in terms of risk and gap acceptance using agent-based modeling techniques.
Khaled Shaaban, Karim Abdelwarith
doaj +1 more source