Results 141 to 150 of about 1,879,010 (294)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Global Music Lessons for ages 7-11
, 2007 Designed to tie in with Oxjam, these activities celebrate music from across the globe. Choose from numerous stand-alone lessons, offering opportunities for singing, performing, composing, improvising, listening, and appraising.
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Global Music Lessons for ages 11-14
, 2007 Designed to tie in with Oxjam, these activities celebrate music from across the globe. Choose from numerous stand-alone lessons, offering opportunities for singing, performing, composing, improvising, listening, and appraising.
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Rational Surface Engineering Reduces Advanced Glycation End-Product Adsorption and Improves Implant Integration. [PDF]
Adv Sci (Weinh)Le TN +13 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
State and society in the early Middle Ages: the Middle Rhine Valley, 400–1000
, 2006 Book synopsis: This book shows just how much can be discovered about the so-called "Dark Ages," between the fall of Rome and the high Middle Ages. Whereas it is believed widely that the source materials for early medieval Europe are too sparse to allow ...
Innes, Matthew
core
The role of oxygen in the formation of fluorescent advanced glycation end products from α-dicarbonyl compounds. [PDF]
Z Gerontol GeriatrGhaffari Makhmalbaf P, Simm A.
europepmc +1 more source