Results 121 to 130 of about 1,879,010 (294)
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Global Citizenship: Activities for Ages 7-11
Try these classroom activities on global citizenship themes for learners aged 7-11. Build an understanding of social justice, equality and sustainability within the existing curriculum. Support learners to recognise how interconnected our world is and
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Time series of monthly confirmed malaria cases, slide positivity rate, admissions and deaths extracted by use of a Hodrick-Prescott filter with monthly smoothing parameter λ = 14,400 (HP = Hodrick-Prescott filter; MAl-IPDAll Ages = Inpatient malaria ...
Meseret Aseffa Yenehun (663156) +13 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The High Arctic Large Igneous Province (HALIP) formed in the circum‐Arctic during the Cretaceous. The timing and duration of emplacement of these mafic magmas are important for understanding the climatic and environmental effects, yet many uncertainties ...
A. M. R. Sartell +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A Method for Estimating Size of Population Aged 90 and over with Application to the U.S. Census 2000 Data [PDF]
In many countries population estimates are unreliable at higher ages. In this article a method for producing an independent estimate of population aged 90+ from data on deaths and population estimates at lower ages is developed.
Kirill F. Andreev
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