Results 111 to 120 of about 1,841,120 (284)

A Review of the Spatiotemporal Evolution of the High Arctic Large Igneous Province, and a New U‐Pb Age of a Mafic Sill Complex on Svalbard

open access: yesGeochemistry, Geophysics, Geosystems
The High Arctic Large Igneous Province (HALIP) formed in the circum‐Arctic during the Cretaceous. The timing and duration of emplacement of these mafic magmas are important for understanding the climatic and environmental effects, yet many uncertainties ...
A. M. R. Sartell   +4 more
doaj   +1 more source

Medieval Stained Glass: Text and Context

open access: yes, 2006
Lecture held April 4, 2006, 7 p.m. in Woodward Hall, UNM as the third lecture of the Institute for Medieval Studies' Spring Lecture Series 2006.The development of a method for creating stained glass windows was one of the outstanding technical ...
Raguin, Virginia Chieffo
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Antiglycating activity of biomimetically synthesized magnetic copper ferrite nanoparticles: inhibition of methylglyoxal-derived AGEs

open access: yesFrontiers in Nanotechnology
The nonenzymatic glycation process initiates a harmful cycle that generates various intermediate compounds, leading to carbonyl and oxidative stress, and ultimately resulting in the formation of advanced glycation end products (AGEs).
Saheem Ahmad   +10 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Dietary Intake of Processed Meats with Fermented Foods: Effects on Carcinoembryonic Antigen, Hematological Parameters, and Gut Microbiota of Adult and Elderly Mouse Models

open access: yesFood Science of Animal Resources
This study analyzed the effects of the dietary intake of processed meat products (ham, sausage, and bacon) with fermented foods (kimchi, soybean paste and red pepper paste) on colorectal cancer (CRC) risk, hematological parameters, and gut microbiota of ...
Seung Yun Lee   +7 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Global Citizenship: Activities for Ages 5-7

open access: yes, 2007
Try these classroom activities on global citizenship themes for learners aged 5-7. Develop an understanding of social justice, equality and sustainability within the existing curriculum. Explore concepts such as 'rich' and 'poor', our similarities and

core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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