Results 61 to 70 of about 5,821 (279)

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

New certificateless aggregate signature scheme with universal designated verifier

Tongxin xuebao, 2017
Certificateless aggregate signature(CLAS) schemes with universal designated verifier had been widely applied in resource-constrained wireless mobile networks,because they could not only solve the problems of the certificate management and private key ...
Zhi-yan XU, Li-bing WU, Li LI, De-biao HE   +3 more
doaj   +2 more sources

Anonymous Certificateless Aggregate Signature Scheme in VANETs [PDF]

Jisuanji gongcheng
Vehicle Ad-Hoc Networks(VANETs) serve as the foundational infrastructure for future intelligent traffic systems, which will help ensure the safe operation of vehicles. However, in an open wireless communication mode and complex communication environment,
GUO Rui, HU Guoliang, WANG Junming
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Efficient anonymous roaming authentication scheme using certificateless aggregate signature in wireless network

Tongxin xuebao, 2016
To solve the privacy-preserving problem during the roaming authentication of wireless mobile networks, a novel roaming authentication scheme with anonymity was presented.
Dan LIU, Run-hua SHI, Shun ZHANG, Hong ZHONG   +3 more
doaj   +2 more sources

A Lightweight Certificateless Aggregate Ring Signature Scheme for Privacy-preserving in Smart Grids [PDF]

, 2021
Huiwen Wang, Liangliang Wang, Mi Wen, Kefei Chen, Yiyuan Luo   +4 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

An Efficient Homomorphic Aggregate Signature Scheme Based on Lattice [PDF]

Mathematical Problems in Engineering, 2014
Homomorphic aggregate signature (HAS) is a linearly homomorphic signature (LHS) for multiple users, which can be applied for a variety of purposes, such as multi‐source network coding and sensor data aggregation. In order to design an efficient postquantum secure HAS scheme, we borrow the idea of the lattice‐based LHS scheme over binary field in the ...
openaire   +1 more source