BDMP, a peptide that can penetrate cells and tissues, offering antimicrobial and anti‐inflammatory effects, has been identified as a potential new therapy for periodontitis. ABSTRACT Aim This study evaluated the potential of a beta‐defensin‐3 mimetic peptide (BDMP), a synthetic cell‐penetrating peptide with antimicrobial and immunomodulatory properties,
Beom Soo Jo +13 more
wiley +1 more source
Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source
Aggregatibacter actinomycetemcomitans - osobna iskaznica paradontopatogena
A.a. je nepokretni, spororastući, kapnofilni (zahtjeva atmosferu s povećanim koncentracijom CO2), Gram-negativni kokobacil. Raste sporo na temperaturi od 37°C, u aerobnim ili anaerobnim uvjetima, u tekućim i čvrstim medijima, u atmosferi s otprilike 5% CO2.
Musić, Larisa, Puhar, Ivan
openaire +3 more sources
Proteomics of Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles
Aggregatibacter actinomycetemcomitans is an oral and systemic pathogen associated with aggressive forms of periodontitis and with endocarditis. Outer membrane vesicles (OMVs) released by this species have been demonstrated to deliver effector proteins such as cytolethal distending toxin (CDT) and leukotoxin (LtxA) into human host cells and to act as ...
Kieselbach, Thomas +3 more
openaire +5 more sources
Peri‐Implantitis and Periodontitis: Biological Convergence, Contextual Divergence
Periodontal and peri‐implant tissues differ and coincide in many aspects, from the clinical and radiological perspective, including histology, microbiology, and molecular markers. Thus, health and disease may also follow different and similar routes.
Pablo Galindo‐Moreno +6 more
wiley +1 more source
Examination of maternal gingival crevicular fluid for the presence of selected periodontopathogens implicated in the pre-term delivery of low birthweight infants [PDF]
Background: Reports show that more than 20 million infants world-wide are born prematurely with 95% of all pre-term births occurring in developing countries.
Africa, Charlene W.J. +2 more
core +1 more source
Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang +3 more
wiley +1 more source
Oral Microbiome in Systemic Autoimmune Diseases: A Systematic Review
ABSTRACT Objective The oral cavity represents a key but underexplored interface between host immunity and microbial communities. The aim of this systematic review was to synthesize current literature on oral microbiota alterations in systemic autoimmune diseases.
Sophie Jung +2 more
wiley +1 more source
Aggregatibacter actinomycetemcomitans LPS binds human interleukin-8
Various gram-negative species sequester host cytokines using outer membrane proteins or surface modulation by sulfated polysaccharides. An outer membrane lipoprotein (BilRI) of the periodontal pathogen Aggregatibacter actinomycetemcomitans binds several ...
Tuuli Ahlstrand +4 more
doaj +1 more source
Designing Polymerase Chain Reaction for Molecular Diagnostics of the Primary Bacterial Cause of Periodontitis [PDF]
Background & Objective: Periodontal disease, which can become a chronic condition, is an inflammatory disease that upsets the soft and hard structures supporting the teeth. The aim of the present study was to design and develop an in-house PCR Method, to
mohammad soleimani +2 more
doaj

