Results 91 to 100 of about 130,584 (298)

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Agile Game: A Project Management Game for Agile Methods

Since mid-1990s, companies have adopted agile methods and incorporated them in their development methodologies. For this reason, future project managers and developers need to have a full understanding of these methods.
Gkritsi, Aikaterini
core   +1 more source

Association of Non-specific Mechanical low Back Pain with Limited Ankle Dorsiflexion among Female Students

Journal Riphah College of Rehabilitation Sciences
Background: Mechanical low back pain is the pain in the lumbar area caused by aberrant stresses on the spine's vertebrae, ligaments, soft tissues, intervertebral discs, muscles and other soft tissues Objective: To determine the association between non ...
Muhammad Hafeez, Faiqa Tariq, Muhammad Irfan Sattar, Arsalan Saeed, Shabana Rahim, Mohammad Waqas Ghauri   +5 more
doaj  

A Modular Variable Stiffness Co‐Bot System Achieving Tasks Flexibility and Contact Compliance

Advanced Science, EarlyView.
Bio‐inspired antagonistic compliance enables a modular rigid‐soft co‐bot platform with variable stiffness for safe human‐robot interaction (HRI): Standardized interfaces support application‐driven configurations with tailored DoFs, workspace, and stiffness range, making the system suited to HRI and low‐volume automation.
Wenlong Gaozhang, Yue Li, Jialei Shi, Yaxi Wang, Kaspar Althoefer, Agostino Stilli, Helge A. Wurdemann   +6 more
wiley   +1 more source

Designing distribution centres for agile supply chains [PDF]

, 2006
Increasing globalisation and market volatility represent major challenges for many supply chains, and particularly for the distribution centres within them. This paper examines how distribution centres are being designed to be agile even though they are,
Baker, Peter
core   +1 more source

MoveLab^®: Validation and Development of Novel Cross-Platform Gait and Mobility Assessments Using Gold Standard Motion Capture and Clinical Standard Assessment

Sensors
Wearable health assessment devices enable real-time clinical- and home-based patient monitoring. Human gait analysis is a widely accepted musculoskeletal assessment.
Katie Powell, Ahmad Amer, Zornitza Glavcheva-Laleva, Jenny Williams, Caomhnad O’Flaherty Farrell, Finchley Harwood, Peter Bishop, Catherine Holt   +7 more
doaj   +1 more source

Extracellular Enzymes and Antimicrobial Activities of Celluloytic Bacteria from the Gut of Black Surgeonfish (Acanthurus gahhm)

Annals of Tropical Research, 2017
The diverse microflora of the gastrointestinal tracts of fish is a promising frontier for the discovery of beneficial bacteria and further microbiological investigations.
Francis S. Legario, Agile J. Pesina
doaj   +1 more source

MOF‐Derived Cu‐TiO2/Alginate Micromotors for Buoyancy‐Regulated 3D Motion

Advanced Science, EarlyView.
In this work, cyanobacteria‐inspired sodium alginate (SA)/Cu‐TiO2/Fe3O4 hydrogel micromotors generate and encapsulate O2 microvesicles upon light irradiation, enabling buoyancy‐mediated Z‐axis upward migration and surface enrichment at the light‐exposed water‐air surface.
Wei Zou, Qing Wu, Jiawei Lin, Kunchen Li, Yulong Ying, Josep Puigmartí‐Luis, Salvador Pané, Sheng Wang   +7 more
wiley   +1 more source

Micro/Nanoscale Acoustic Manipulation: From Particle Control to Autonomous Microswimmers

Advanced Science, EarlyView.
This conceptual framework illustrates acoustic technology as a multifunctional platform enabling passive particle manipulation across scales and autonomous propulsion of microswimmers. ABSTRACT Acoustic manipulation and propulsion technologies have emerged as powerful platforms for micro/nanoscale control, enabled by their non‐contact operation, label ...
Jiahui Chu, Lemin Zhang, Xu Wang, Wenzong Li, Yahua Liu   +4 more
wiley   +1 more source

Toward Constitutional Autonomy in AI Systems: A Theoretical Framework for Aligned Agentic Intelligence

IEEE Access
This paper introduces Constitutional Autonomy, extending AI alignment beyond training-phase optimization into runtime enforcement for autonomous agentic systems.
William Torgbi Agbemabiese
doaj   +1 more source