Results 81 to 90 of about 358,049 (342)

Управління міжнародним бізнесом: Agility Journey для високотехнологічних компаній [PDF]

open access: yes, 2019
The purpose of the article is the development of recommendations for the business maturity determination and measurement in the implementation of the agile approach for high-tech companies.
Rusanova, L. D.   +1 more
core  

Gait Analysis of Pak Biawak: A Necrobot Lizard Built using the Skeleton of an Asian Water Monitor (Varanus Salvator)

open access: yesAdvanced Robotics Research, EarlyView.
Pak Biawak, a necrobot, embodies an unusual fusion of biology and robotics. Designed to repurpose natural structures after death, it challenges conventional boundaries between nature and engineering. Its movements are precise yet unsettling, raising questions about sustainability, ethics, and the untapped potential of biointegrated machines.
Leo Foulds   +2 more
wiley   +1 more source

AGILE detection of GeV gamma-ray emission from the SNR W28

open access: yes, 2010
Supernova remnants (SNRs) are believed to be the main sources of Galactic cosmic rays. Molecular clouds associated with SNRs can produce gamma-ray emission through the interaction of accelerated particles with the concentrated gas.
A. Argan   +77 more
core   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

open access: yesAdvanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li   +15 more
wiley   +1 more source

A Review on Biodegradable Materials of Sustainable Soft Robotics and Electronics

open access: yesAdvanced Science, EarlyView.
Biodegradable materials are gaining increasing attention in soft robotics and electronics due to their environmental friendliness, showing great potential for sustainability. In this review, the classification of biodegradable materials, their applications in the field of soft robotics and electronics, as well as the challenges and future prospects ...
Yizhu Xie   +8 more
wiley   +1 more source

Necessity of Inverted Supports in the Inclined Strut Section of the Foundation Pit with Strip Bottom Plate and Diaphragm Wall

open access: yesChengshi guidao jiaotong yanjiu
[Objective] In order to save project investment, strip bottom plates that are not fully closed are used for the foundation pit bottom sealing in some foundation pit inclined strut sections. After the removal of the lowest supports in such foundation pits,
YANG Kaiwu   +4 more
doaj   +1 more source

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

open access: yesAdvanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang   +14 more
wiley   +1 more source

CRISPR-Cas9/Cas12a systems for efficient genome editing and large genomic fragment deletions in Aspergillus niger

open access: yesFrontiers in Bioengineering and Biotechnology
CRISPR technology has revolutionized fungal genetic engineering by accelerating the pace and expanding the feasible scope of experiments in this field. Among various CRISPR-Cas systems, Cas9 and Cas12a are widely used in genetic and metabolic engineering.
Guoliang Yuan   +13 more
doaj   +1 more source

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

open access: yesAdvanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu   +13 more
wiley   +1 more source

Framework for Agile Transformation: Guiding Organizations Through Cultural, Structural, and Competency Shifts in Project Management

open access: yesAdministrative Sciences
This paper aims to provide a framework for guiding organizations toward Agile practices for project management. Through a case study analysis conducted in an information technology company, the paper aims to explore the interplay between current ...
Valentina Ndou   +2 more
doaj   +1 more source

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