Results 91 to 100 of about 2,734,594 (261)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Aging Resistance Evaluation of an Asphalt Mixture Modified with Zinc Oxide

Infrastructures
The phenomenon of the oxidation and aging of asphalt binders affects the strength and durability of asphalt mixtures in pavements. Several studies are trying to improve the resistance to this phenomenon by modifying the properties of the binders with ...
Hugo Alexander Rondón-Quintana, Carlos Alfonso Zafra-Mejía, Carlos Felipe Urazán-Bonells   +2 more
doaj   +1 more source

Be the voice. Take action. Tigether

, 2012
Jan. 12, 2012-; "... A blog-like publication that connects interest Ohioans to news and information about issues affecting older Ohioans and the people who care for and serve them."; Not published Feb.-Nov. 2013.; Issue for Jan.
Western Reserve Area Agency on Aging, Perkins, Fatima   +1 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Other title: Kansas State Advisory Council on Aging annual report, 1992; Other title: Kansas Advisory Council on Aging annual report, 1992 Other title: Title of report quoted from Council Chair's letter of transmittal to Governor Finney, et al.: 1992-93 Annual Report of the Kansas State Advisory Council on Aging

, 1994
"I am happy to present to you the 1992-93 Annual Report of the Kansas State Advisory Council on Aging"."--[February 3, 1994 Cover letter from Charles Oldfather, Chair of the Council, to Governor Finney et al.]<br>Created in 1977 by the Kansas Act ...
Kansas Advisory Council on Aging.
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

[Coalition for Aging LGBT General Preparation Resources]

Coalition for Aging LGBT General Preparation Resources document from the Coalition for Aging LGBT Records (The Dallas Way)
Coalition for Aging LGBT
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Study on Antiaging Performance of Graphene Oxide–Modified Guss Asphalt

Advances in Materials Science and Engineering
The mixing temperature of the guss asphalt mixture is generally 220°C–240°C during production, and the mixture needs to be heated and stirred during transportation, which puts forward higher requirements for the antiaging ability of asphalt.
Yong Yang, Tengda Dong, Fang Liu, Aozhe Liu, Yixuan Li   +4 more
doaj   +1 more source