Results 241 to 250 of about 1,168,781 (390)

Influence of circulating alpha adrenoceptor agonists on lung function in patients with exercise induced asthma and healthy subjects. [PDF]

, 1986
Kjell Larsson, Arne Martinsson, Paul Hjemdahl   +2 more
openalex   +1 more source

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1–polarizing program in dendritic cells

Nature Immunology, 2005
G. Napolitani, A. Rinaldi, F. Bertoni, F. Sallusto, A. Lanzavecchia   +4 more
semanticscholar   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

Studies in the Primate on the Analgetic Effects Associated with Intrathecal Actions of Opiates,α-Adrenergic Agonists and Baclofen

, 1981
Tony L. Yaksh, Sakamuri V. Reddy
openalex   +1 more source

Increased sensitivity of fat cell adenylate cyclase to stimulatory agonists during fasting is not related to impaired inhibitory coupling system [PDF]

, 1986
Danièle Lacasa, Brigitte Agli, Yves Giudicelli   +2 more
openalex   +1 more source

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides.

Biochemical Journal, 1983
M. Berridge, R. Dawson, C. Downes, J. P. Heslop, R. Irvine   +4 more
semanticscholar   +1 more source

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

Advanced Science, EarlyView.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang, Yujie Shan, Shihong Xu, Jing Wang, Meng Luo, Jiaojiao Zhou, Qishan Chen   +6 more
wiley   +1 more source

Toll-like receptor 2 activation of early divided bovine embryo promotes its viability and development competence in vitro. [PDF]

Sci Rep
Ma D, Akthar I, Hashimoto T, Marey MA, Kusama K, Imakawa K, Shimada M, Miyamoto A.   +7 more
europepmc   +1 more source

PIEZO1‐GPX4 Axis Mediates Mechanical Stress‐Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation

Advanced Science, EarlyView.
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen, Fushuai Peng, Shuqing Chen, Yukun Du, Jianyi Li, Yuanyuan Fan, Zichen Cui, Guanghui Gu, Han Zhang, Zhensong Jiang, Guodong Wang, Xingzhi Jing, Jun Dong, Tao Li, Yongming Xi   +14 more
wiley   +1 more source

An Agonist of Zinc-Sensing G-Protein Coupled Receptor 39 Accelerates Skin Wound Healing and Protects Against UVB-Induced Keratinocyte Damage. [PDF]

J Exp Pharmacol
Chatkul P, Wongsawat M, Satianrapapong W, Arinno A, Lamlertthon P, Wachapatthana U, Sucharitakul T, Wachiradejkul W, Sakulpanich D, Petcharat B, Chancharoen W, Liamsuwan T, Pongkorpsakol P.   +12 more
europepmc   +1 more source