Results 251 to 260 of about 847,478 (341)

The 5-hydroxytryptamine(4a) receptor is palmitoylated at two different sites and acylation is critically involved in regulation of receptor constitutive activity [PDF]

, 2002
Bickmeyer, Ulf, Dumuis, A., Heine, M., Loubert, L., Ponimaskin, E. G., Richter, D. W., Sebben, M.   +6 more
core  

KIF23 silencing suppresses papillary thyroid carcinoma metastasis by regulating mitophagy via Wnt/β-catenin pathway. [PDF]

Endocr Connect
Liu Y, Zhang J, Chen Y, Zhu M, Chen W, Hao Z, Deng Y, Han X, Xu J.   +8 more
europepmc   +1 more source

Targeting HDAC and PARP Enhances STING‐Dependent Antitumor Immunity in STING‐Deficient Tumor

Advanced Science, EarlyView.
Dual HDAC and PARP inhibition restores STING signaling, enhances interferon response, and boosts antitumor immunity in STING‐deficient tumors. . Abstract The stimulator of interferon genes (STING)‐mediated innate immune pathway plays an important role in tumor immunosurveillance.
Chengzhou Mao, Weiwen Fan, Jiaqi Liu, Fangzhou Yang, Wenkai Li, Lulu Li, Zhichao Shi, Qinyuan Li, Zigao Yuan, Yuyang Jiang, Bizhu Chu   +10 more
wiley   +1 more source

Danazol but not gonadotropin-releasing hormone agonists suppresses autoantibodies in endometriosis

, 1988
Albert El-Roeiy, W. Paul Dmowski, Norbert Gleicher, Ewa Radwańska, Lisa A. Harlow, Zvi Binor, Ian S. Tummon, Richard G. Rawlins   +7 more
openalex   +1 more source

Investigation of the heterogeneity of cancer cells using single cell Ca²⁺ profiling. [PDF]

Cell Commun Signal
Bura AE, Caussette C, Guéguinou M, Bellanger D, Robert A, Cancel M, Lacouette-Rata M, Fromont G, Vandier C, Mahéo K, Brouard T, Crottès D.   +11 more
europepmc   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

Advanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan, Mengyao Zhang, Haiyue Guo, Yan Xu, Chenjie Xu, Fan Hu, Yinbing Pan, Xian Wang, Wentao Liu, Chun‐Yi Jiang   +9 more
wiley   +1 more source

Use of luteinising hormone-releasing hormone agonist (leuprorelin) in advanced post-menopausal breast cancer: clinical and endocrine effects

, 1989
I.L. Crighton, Mitch Dowsett, A. Lal, A. Man, IE Smith   +4 more
openalex   +1 more source

GLP-1 receptor agonism results in reduction in hepatic ethanol metabolism. [PDF]

NPJ Metab Health Dis
Zahrawi F, Suyavaran A, Banini BA, Mehal WZ.   +3 more
europepmc   +1 more source

Targeted Expansion of Treg Cells to Induce Immune Tolerance after Kidney Transplantation

Advanced Science, EarlyView.
A dual‐targeting nanoparticle platform that selectively engages graft stromal cells via CD248 receptors while employing kidney‐ specific promoters (NPHS2) to drive localized IL‐ 2/TGF‐βexpression is developed. This approach achieves three therapeutic objectives:1) intragraft Treg polarization without systemic cytokine exposure;2) reduced dependence on ...
Tong Lu, Hongtao Song, Limin He, Zhihao Hu, Yu Li, Chao Xu, Shaojie Liu, Jun Jiang, Yike Zhou, Zhengxuan Li, Zeyu Li, Keying Zhang, Shuaijun Ma, Ruochen Qi, Shichao Han, Changhong Shi, Weihong Wen, Donghui Han, Weijun Qin   +18 more
wiley   +1 more source

Does constant infusion of gonadotropin-releasing hormone agonist lead to greater suppression of gonadal function in man than its intermittent administration?

, 1985
Shalender Bhasin, Barbara Steiner, Ronald S. Swerdloff   +2 more
openalex   +1 more source