Results 1 to 10 of about 32,179 (263)

A systematic review and pharmacovigilance analysis of the risk of agranulocytosis associated with metamizole use. [PDF]

Sci Rep
Metamizole is an analgesic widely used after its introduction but later withdrawn in several countries due to the risk of agranulocytosis. Despite this, it remains frequently used worldwide.
Zinzi A, Gaio M, Ruggiero D, Riccardi C, Cagnotta C, Pentella C, Capuano A, Rafaniello C.   +7 more
europepmc   +2 more sources

Drug-induced agranulocytosis: Case series [PDF]

Hospital Pharmacology, 2018
Introduction: Agranulocytosis is a life-threatening disorder characterized by disappearance of granulocytes from peripheral blood or decrease of peripheral neutrophil count below 0.5x109 /l. It frequently occurs as idiosyncratic adverse drug reaction. It
Čolović Nataša R., Leković Danijela R., Stojković-Lalošević Milica LJ.   +2 more
doaj   +2 more sources

Predicting clozapine-induced adverse drug reaction biomarkers using machine learning. [PDF]

Sci Rep
Clozapine is an atypical antipsychotic used for patients with treatment-resistant schizophrenia. This drug has serious adverse drug reactions (ADRs), including the risk of severe neutropenia (agranulocytosis).
Cooper JP, Chue P, Siraki AG, Tonoyan L.
europepmc   +2 more sources

Ceftazidime-Induced Agranulocytosis: A Case Report. [PDF]

Clin Case Rep
The most common adverse events associated with ceftazidime include hypersensitivity reactions, gastrointestinal disturbances, and transient abnormal liver function tests, whereas neutropenia is a rare complication.
Dong B, Wu X, Huang C.
europepmc   +2 more sources

Drug Agranulocytosis

Общая реаниматология, 2010
The paper covers the problem associated with the wide availability and uncontrolled use of over-the-counter medicines, particularly analgesics, antipyretics, and anticatarrhal agents, which lead to the occurrence of adverse drug reactions and poisonings ...
A. V. Polunina, A. V. Vlasenko, V. V. Moroz, V. N. Yakovlev, V. G. Alekseyev   +4 more
doaj   +3 more sources

A case of idiosyncratic drug-induced agranulocytosis because of sulbactam/ampicillin. [PDF]

J Gen Fam Med
Idiosyncratic drug‐induced agranulocytosis is a rare but life‐threatening condition that requires immediate medical intervention. Although sulbactam/ampicillin (SBT/ABPC) is a widely used antibiotic, no prior case reports of its associated ...
Toda K, Kuroda K, Kuroda M, Kawai K, Sato Y.   +4 more
europepmc   +2 more sources

Durvalumab induced immune-related agranulocytosis after conversion surgery in a patient with intrahepatic cholangiocarcinoma: a case report. [PDF]

Front Immunol
Kitamura Y, Shimizu S, Kuroda S, Honmyo N, Nakano R, Sakai H, Tahara H, Ohira M, Ide K, Kobayashi T, Ichinohe T, Ohdan H.   +11 more
europepmc   +3 more sources

HLA-DQB1 6672G>C (rs113332494) is associated with clozapine-induced neutropenia and agranulocytosis in individuals of European ancestry

Translational Psychiatry, 2021
The atypical antipsychotic clozapine is the only effective medication for treatment-resistant schizophrenia. However, it can also induce serious adverse drug reactions, including agranulocytosis and neutropenia.
Bettina Konte, James T. R. Walters, Dan Rujescu, Sophie E. Legge, Antonio F. Pardiñas, Dan Cohen, Munir Pirmohamed, Jari Tiihonen, Annette M. Hartmann, Jan P. Bogers, Jan van der Weide, Karen van der Weide, Anu Putkonen, Eila Repo-Tiihonen, Tero Hallikainen, Ed Silva, Oddur Ingimarsson, Engilbert Sigurdsson, James L. Kennedy, Patrick F. Sullivan, Marcella Rietschel, Gerome Breen, Hreinn Stefansson, Kari Stefansson, David A. Collier, Michael C. O’Donovan, Ina Giegling   +26 more
doaj   +1 more source

Distinctive pattern of neutrophil count change in clozapine-associated, life-threatening agranulocytosis

npj Schizophrenia, 2022
The wider use of clozapine is limited by the risk of agranulocytosis and the associated requirement for monitoring of neutrophil counts. We searched local electronic patient records for cases of agranulocytosis occurring during clozapine treatment during
David Taylor, Kalliopi Vallianatou, Eromona Whiskey, Olubanke Dzahini, James MacCabe   +4 more
doaj   +1 more source

Agranulocytosis induced by metamizole and its management with granulocyte growth factor [PDF]

Vojnosanitetski Pregled, 2005
Drug-induced agranulocytosis was defined as a severe selective neutropenia caused by an unexpected drug reaction. Metamizole was the most common nonopioid analgesic drug associated with agranulocytosis.
Čeleketić Dušica, Trpković Andreja, Cvetković Zorica   +2 more
doaj   +1 more source