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Iron accumulation in hypothalamus promotes age-dependent obesity and metabolic dysfunction of male mice. [PDF]

open access: yesMol Biomed
Wang X   +8 more
europepmc   +1 more source

Lac-Phe induces hypophagia by inhibiting AgRP neurons in mice. [PDF]

open access: yesNat Metab
Liu H   +29 more
europepmc   +1 more source
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mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior

Biochemical and Biophysical Research Communications, 2015
Orexigenic agouti-related protein/neuropeptide Y (Agrp/NPY) neurons and an orexigenic pro-opiomelanocortin (POMC) neurons of the hypothalamus regulate feeding behavior and energy homeostasis. An understanding of the molecular signaling pathways that regulate Agrp/NPY and POMC function could lead to novel treatments for metabolic disorders.
Michael N Hall, Verena Albert
exaly   +5 more sources

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