Results 101 to 110 of about 7,077 (114)

Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons

Nature Neuroscience, 1998
Neuropeptide Y (NPY) stimulates food intake and promotes weight gain, whereas melanocortins have the opposite effect. Yet both peptides are synthesized in the arcuate nucleus, a hypothalamic area involved in energy homeostasis. We report here that mRNA encoding NPY and the melanocortin precursor, proopiomelanocortin (POMC) are expressed in adjacent ...
T M, Hahn, J F, Breininger, D G, Baskin, M W, Schwartz   +3 more
openaire   +2 more sources

The Role of AGRP in Regulating Dopaminergic Neurons in the Brain

Neuroscience and Behavioral Physiology, 2015
Immunoreactive processes containing agouti-regulated protein (AGRP) were detected in various dopaminergic structures in the brains of rats and mice. Double immunolabeling demonstrated the presence of AGRP-immunoreactive processes around the bodies of dopaminergic neurons.
A. L. Mikhrina, I. V. Romanova
openaire   +1 more source

Regulation of orexigenic AgRP neurons: A third way?

Trends in Endocrinology & Metabolism, 2015
Arcuate AgRP neurons are critical for food intake. Two pathways leading to AgRP neuron activation and food intake include regulation by peripheral hormones leptin and ghrelin, and neuronal regulation via glutamatergic inputs. In a recent article in Cell Reports, Yang et al. demonstrate 'a third way,' regulation by resident astrocytes.
Nathan C, Bingham, Roger D, Cone
openaire   +2 more sources

314-OR: Mechanisms of AgRP Neuron-Induced Hunger

Diabetes, 2019
Neural circuits express a remarkable diversity of neuropeptides, yet the specific function of most of these peptides remains unclear. Agouti-Related Peptide (AgRP) neurons in the arcuate nucleus are critical for the regulation of energy balance. These cells are activated by food deprivation and their activity promotes food seeking and consumption. When
openaire   +1 more source

[A role of AGRP on dopamine brain neurons regulation].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2014
In rats and mice in different dopaminergic brain structures the immunoreactive axons with agouti-related protein (AGRP) were identified. The double immunofluorescence method shows the presence of AGRP-immunoreactive processes around the bodies of dopaminergic neurons.
A L, Mikhrina, I V, Romanova
openaire   +1 more source

Agrp-negative arcuate NPY neurons drive feeding under positive energy balance via altering leptin responsiveness in POMC neurons

Cell Metabolism, 2023
Nicola J Lee, Chi Kin Ip, Ramon O Tasan
exaly  

Functional Ontogeny of Hypothalamic Agrp Neurons in Neonatal Mouse Behaviors

Cell, 2019
Marcelo R Zimmer, Rafael Dai Pra, Marcelo O Dietrich   +2 more
exaly  

Simultaneous targeting of POMC and AgRP neurons

Nature Metabolism
openaire   +2 more sources

A Small Potassium Current in AgRP/NPY Neurons Regulates Feeding Behavior and Energy Metabolism

Cell Reports, 2016
Yanlin He, Gang Shu, Yongjie Yang
exaly  

Loss of GABAergic Signaling by AgRP Neurons to the Parabrachial Nucleus Leads to Starvation

Cell, 2009
Qi Wu, Richard D Palmiter
exaly