Atypical hemolytic uremic syndrome in a patient with thalassemia and a CFH gene mutation: a case report [PDF]
Frontiers in MedicineAtypical hemolytic uremic syndrome (aHUS) is a complement-associated thrombotic microangiopathy (TMA). Thalassemia is a hemolytic anemia triggered by defects in the beta-globin gene. Mutations in the complement factor H (CFH) gene are associated with the
Jing Wu +6 more
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Reply to Letter: "Limitations of Complement Activity Assays as Biomarkers for Ravulizumab Therapeutic Monitoring" by Saccà and Pelto Regarding "Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab". [PDF]
Ann Clin Transl NeurolAnnals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1303-1304, June 2026.
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Case Report: Effective use of eculizumab in treating recurrent atypical HUS following renal transplantation triggered by SARS-CoV-2 infection [PDF]
Frontiers in MedicineAtypical hemolytic uremic syndrome (aHUS) is a severe post-transplant complication associated with a high risk of graft loss and mortality. Based on its pathophysiological mechanism, aHUS can be classified into recurrent aHUS (reactivation post ...
Zhe Yang +7 more
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Recurrent hemolytic uremic syndrome caused by gene mutation: a case report [PDF]
Childhood Kidney Diseases, 2022 Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury without any association with preceding diarrhea.
Baek Sup Shin +2 more
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BMC Cancer, 2022 Background Axillary lymph node (LN) metastasis is one of the most important predictors of recurrence and survival in breast cancer, and accurate assessment of LN involvement is crucial.
Joana Reis +9 more
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Atypical Hemolytic Uremic Syndrome in a 13-year-old Lao Girl: A Case Report [PDF]
Childhood Kidney Diseases, 2019 Atypical hemolytic uremic syndrome (aHUS), a rare form of thrombotic microangiopathy, is distinguished from the typical form by the absence of a preceding verotoxin-producing Escherichia coli infection. Notably, aHUS occurs in association with genetic or
Philavanh Kedsatha +2 more
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The evaluation of a scoring system for diagnosing atypical hemolytic uremic syndrome
Thrombosis Update, 2020 Objective: Although the definitive diagnosis of atypical hemolytic uremic syndrome (aHUS) depends on a genetic analysis for the complement factors, such a genetic analysis is time-consuming and expensive.
Hideo Wada +5 more
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Atypical hemolytic uremic syndrome and eculizumab therapy in children [PDF]
Korean Journal of Pediatrics, 2018 Hemolytic uremic syndrome (HUS) is often encountered in children with acute kidney injury. Besides the well-known shiga toxin-producing Escherichia coli-associated HUS, atypical HUS (aHUS) caused by genetic complement dysregulation has been studied ...
Seong Heon Kim +2 more
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Atypical hemolytic uremic syndrome: a pediatric case report
Zdorovʹe Rebenka, 2023 Background. Atypical hemolytic uremic syndrome (aHUS) is an extremely rare but life-threatening disorder in children since it may cause acute kidney injury. Patients with aHUS are at risk of recurrence.
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Asian Journal of Transfusion Science, 2022 Atypical hemolytic uremic syndrome (aHUS) is a rare and life-threatening disease that is associated with high mortality and morbidity. The incidence of aHUS is about 1 or 2 cases per 1,000,000 per year. Etiology can be either familial or sporadic.
Ashwinkumar Vaidya +5 more
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