Results 141 to 150 of about 22,661 (290)

NLRP3 and AIM2 inflammasomes expression is modified by LPS and titanium ions increasing the release of active IL-1β in alveolar bone-derived MSCs

Stem Cells Translational Medicine
Periodontitis and peri-implantitis are inflammatory diseases of infectious etiology that lead to the destruction of the supporting tissues located around teeth or implants.
Ana Belén Carrillo-Gálvez, Federico Zurita, José Antonio Guerra-Valverde, A. Aguilar-González, Darío Abril-García, M. Padial-Molina, A. Olaechea, Natividad Martín-Morales, Francisco Martín, Francisco O'Valle, Pablo Galindo- Moreno   +10 more
semanticscholar   +1 more source

Assembly mechanism of the AIM2 inflammasome sensor revealed by single-molecule analysis [PDF]

, 2022
Meenakshi Sharma, Eva de Alba
openalex   +1 more source

AIM2 inflammasome mediates Arsenic-induced secretion of IL-1 β and IL-18 [PDF]

, 2016
Mingfang Zhang, Yuanlin Qi, Hui Li, Jiajun Cui, Lu Dai, Jacqueline A. Frank, Jian Chen, Wenhua Xu, Gang Chen   +8 more
openalex   +1 more source

Dihydroartemisinin inhibits activation of the AIM2 inflammasome pathway and NF-κB/HIF-1α/VEGF pathway by inducing autophagy in A431 human cutaneous squamous cell carcinoma cells [PDF]

, 2021
Yajie Wang, Zhijia Li, Muzhou Teng, Junlin Liu   +3 more
openalex   +1 more source

Rolle der Inflammasome NLRP3, NLRC4 und AIM2 bei chronischer Rhinosinusitis

, 2022
Inga Nierkamp, Bektasch Abbaspour, Katrin Stübke, Georg Achim Beule, Maximilian Oberste, Claudia Rudack   +5 more
openalex   +1 more source

AIM2 deletion promotes neuroplasticity and spatial memory of mice

Brain Research Bulletin, 2019
Absent in melanoma 2 (AIM2) senses damaged-associated molecular patterns (DAMPs) and recruits apoptosis speck-like protein (ASC) and caspase-1 to form a molecular platform for cerebral inflammation and neuronal pyroptosis. Here, we found that AIM2 was up-regulated in the hippocampus of 6-months-old APP/PS1 mice and further investigated the role of AIM2
Jian, Chen, Shu, Shu, Yanting, Chen, Zhuo, Liu, Linjie, Yu, Lixuan, Yang, Yun, Xu, Meijuan, Zhang   +7 more
openaire   +2 more sources

Stem cell-derived exosomes prevent the development of thoracic aortic aneurysm/dissection by inhibiting AIM2 inflammasome and pyroptosis

Extracellular Vesicle
Thoracic aortic aneurysm/dissection (TAAD) is a severe vascular condition associated with life-threatening complications, and its underlying molecular mechanisms remain largely unexplored.
Lin Lu, Feng Liu, Weiliang Wu, Yu Zhang, Bin Liu, Qingfang Han, Tonggan Lu, Huiling Zhang, Xi-yong Yu, Yangxin Li   +9 more
doaj   +1 more source

A computationally efficient inorganic atmospheric aerosol phase equilibrium model (UHAERO) [PDF]

, 2005
A variety of thermodynamic models have been developed to predict inorganic gas-aerosol equilibrium. To achieve computational efficiency a number of the models rely on a priori specification of the phases present in certain relative humidity regimes ...
Amundson, N. R., Caboussat, A., He, J. W., Martynenko, A. V., Savarin, V. B., Seinfeld, J. H., Yoo, K. Y.   +6 more
core   +1 more source

Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome [PDF]

, 2021
Liqiu Wang, Tao Liu, Shuai Yang, Lin Sun, Zhiyao Zhao, Li-Yue Li, Yuanchu She, Yanyan Zheng, Xiaoyan Ye, Qing Bao, Guang‐Hui Dong, Chunwei Li, Jun Cui   +12 more
openalex   +1 more source

Roles of a novel splice variant of human IFI16 in innate immune response [PDF]

, 2014
Poster Presentation - Theme 4: Infection & immunityDNA from viral or bacterial pathogens activates innate immune response. The recognition of self-DNA would induce autoimmune diseases such as systemic lupus erythematosus (SLE).
Jin, D, Kok, KH, Siu, KL, Wang, P, Yang, W, Zhang, Y   +5 more
core