Results 161 to 170 of about 22,661 (290)

Hepatocellular carcinoma and AIM2: Therapeutic potential through regulation of autophagy and macrophage polarization

Immunity, Inflammation and Disease
Objective Hepatocellular carcinoma (HCC) poses a significant challenge to global health. Its pathophysiology involves interconnected processes, including cell proliferation, autophagy, and macrophage polarization.
Shuangshuang Xie, Cuiyun Wang, Xiaoyan Liu, Cheng Li, Jinhong Yu, Shumin Ma, Qiang Li, Wenjun Du   +7 more
doaj   +1 more source

Effects of sevoflurane general anesthesia during early pregnancy on AIM2 expression in the hippocampus and parietal cortex of Sprague‑Dawley offspring rats

, 2021
Yulin Zhu, Chao Lv, Jingying Liu, Shujun Shang, Wei Jing   +4 more
openalex   +2 more sources

Mitokondriális eredetű nitrogén szabadgyökök és ATP-függő K-csatornák szerepe az organellum működésében = The involvement of mitochondrial-derived nitrogen radicals and mitoK-ATP channels in the regulation of organelle function [PDF]

, 2009
Elsőként a mitoKATP csatornák alegységeit terveztük azonosítani humán szív mintákon. A kísérletek során megbizonyosodtunk afelől, hogy a korábban ilyen csatornáknak gondolt fehérjék nincsenek jelen megfelelő számban és formában a mitokondriális ...
Csordás, Attila, Horváth, Eszter Mária, Lacza, Zsombor, Pankotai, Eszter, Szabó, Csaba   +4 more
core  

Review of Excessive Cytosolic DNA and Its Role in AIM2 and cGAS-STING Mediated Psoriasis Development

Clinical, Cosmetic and Investigational Dermatology
In psoriasis, keratinocytes are triggered by factors, such as infection or tissue damage, to release DNA, which thereby activates plasmacytoid dendritic cells and macrophages to induce inflammation, thickened epidermis, and parakeratosis. The recognition
Tongtong Xu, Xiaojing Zhong, Nana Luo, Wenyi Ma, P. Hao   +4 more
semanticscholar   +1 more source

A keratinociták, szebociták, és a Propionibacterium acnes baktérium közötti kölcsönhatások in vitro modellezése [PDF]

, 2014
Bőrünk jellegzetes mikrobiális flórával rendelkezik, mely a bőr felső rétegeiben, illetve a piloszebáceus egység (follikulus) területén helyezkedik el. Az itt található sejtek (keratinociták, szebociták) valamint a mikróbák közötti komplex kölcsönhatás ...
Bolla, Beáta Szilvia, Erdei, Lilla, Glasenhardt, Katalin, Kemény, Lajos, Szabó, Kornélia, Tax, Gábor, Urbán, Edit   +6 more
core  

Emodin Inhibits AIM2 Inflammasome Activation via Modulating K27‐Linked Polyubiquitination to Attenuate Renal Fibrosis

Phytotherapy Research
Chronic kidney diseases (CKD) is a serious threat to people's health with renal fibrosis as the major pathological feature. The absent in melanoma 2 (AIM2) has recently been proposed to play a critical role in CKD.
Lidan Lu, Ruonan Shuang, Fang Cao, Zhongwen Sun, Qingxue Wei, Tiantian Gao, Xuejing Gu, Kejian Wen, Xiaolan Cheng, Mingjia Gu   +9 more
semanticscholar   +1 more source

A novel role of AIM2 inflammasome-mediated pyroptosis in radiofrequency ablation of hepatocellular carcinoma

Annals of Hepatology
Introduction and Objectives: The absence of melanoma 2 (AIM2) protein triggers the activation of the inflammasome cascade. It is unclear whether AIM2 plays a role in hepatocellular carcinoma (HCC) and radiofrequency ablation (RFA), which uses ...
Feifan He, Zhongming He, Caoye Wang
doaj   +1 more source

Inhibitory Effects of Ethanol on the NLRP3 Inflammasome [PDF]

, 2015
Immunosuppression is a major complication of alcoholism and contributes to increased rates of opportunistic infections and sepsis associated with the addiction.
Hoyt, Laura Rose
core   +1 more source

AIM2 enhances Candida albicans infection through promoting macrophage apoptosis via AKT signaling

Cellular and Molecular Life Sciences
Candida albicans is among the most prevalent invasive fungal pathogens for immunocompromised individuals and novel therapeutic approaches that involve immune response modulation are imperative.
Qian Jiang, Yayun Chen, Siping Zheng, Lina Sui, Dalang Yu, Furong Qing, Wenji He, Qiuxiang Xiao, Tianfu Guo, Li Xu, Zhichun Liu, Zhiping Liu   +11 more
semanticscholar   +1 more source

AIM2 wt Allele [PDF]

, 2020
openaire   +1 more source