Results 1 to 10 of about 15,388 (248)
Airway microbiome signature accurately discriminates Mycobacterium tuberculosis infection status [PDF]
IScienceSummary: Mycobacterium tuberculosis remains one of the deadliest infectious agents globally. Amidst efforts to control TB, long treatment duration, drug toxicity, and resistance underscore the need for novel therapeutic strategies.
Alex Kayongo, Rogers Sekibira
exaly +5 more sources
The Airway Microbiome at Birth [PDF]
Scientific Reports, 2016 AbstractAlterations of pulmonary microbiome have been recognized in multiple respiratory disorders. It is critically important to ascertain if an airway microbiome exists at birth and if so, whether it is associated with subsequent lung disease. We found an established diverse and similar airway microbiome at birth in both preterm and term infants ...
Charitharth Vivek Lal +2 more
exaly +5 more sources
Airway microbiome-immune crosstalk in chronic obstructive pulmonary disease [PDF]
Frontiers in Immunology, 2023 Chronic Obstructive Pulmonary Disease (COPD) has significantly contributed to global mortality, with three million deaths reported annually. This impact is expected to increase over the next 40 years, with approximately 5 million people predicted to ...
Alex Kayongo +19 more
doaj +6 more sources
Gut Microbes, 2020 Allergic asthma is a highly prevalent inflammatory disease of the lower airways, clinically characterized by airway hyperreactivity and deterioration of airway function.
Irina Spacova +2 more
exaly +4 more sources
Changes in the airway microbiome in patients with bronchiectasis. [PDF]
Medicine (Baltimore), 2023 This study used metagenomic next-generation sequencing (mNGS) technology to explore the changes of the microbial characteristics in the lower respiratory tract in patients with acute exacerbations of bronchiectasis (noncystic fibrosis) to guide clinical treatment and improve patients’ quality of life and prognosis.
Lu D +6 more
europepmc +3 more sources
The airway microbiome and pediatric asthma. [PDF]
Curr Opin Pediatr, 2021 Purpose of review Asthma is the most common chronic disease of childhood. Investigations of the lower and upper airway microbiomes have significantly progressed over recent years, and their roles in pediatric asthma are becoming increasingly clear.
Shah R, Bunyavanich S.
europepmc +3 more sources
Dysglycemia and the airway microbiome in cystic fibrosis. [PDF]
PLoS OneBackground Cystic fibrosis-related diabetes (CFRD) is one of the most common non-pulmonary complications in people living with cystic fibrosis (pwCF), seen in up to 50% of adults. Even when correcting for severity of CFTR mutations, those with CFRD have more pulmonary exacerbations, lower lung function, and increased mortality than those with normal ...
Brenner LN +8 more
europepmc +3 more sources
Changes in the Cystic Fibrosis Airway Microbiome in Response to CFTR Modulator Therapy
Frontiers in Cellular and Infection Microbiology, 2021 The development of CFTR modulator therapies significantly changed the treatment scheme of people with cystic fibrosis. However, CFTR modulator therapy is still a life-long treatment, which is not able to correct the genetic defect and cure the disease ...
Buqing Yi +2 more
exaly +3 more sources
Chronic Obstructive Pulmonary Disease and the Airway Microbiome: What Respirologists Need to Know [PDF]
Tuberculosis and Respiratory Diseases, 2023 Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. The lower airways contain a rich and diverse microbiome, which may play a significant regulatory role in both health and disease.
Don D. Sin
doaj +2 more sources
Predicting BPD: Lessons Learned From the Airway Microbiome of Preterm Infants
Frontiers in Pediatrics, 2020 Bronchopulmonary dysplasia (BPD) is the chronic lung disease of prematurity with an operational definition, various different clinical phenotypes, and a complex, multifactorial etiology.
Samuel J Gentle +2 more
exaly +3 more sources