Results 51 to 60 of about 159,385 (354)

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Challenges in diagnosis and management of central airway obstruction: Case series

SAGE Open Medical Case Reports
Central airway obstruction often presents with respiratory symptoms identical to those of common respiratory diseases. Diagnosis of central airway obstruction is challenging in clinical practice, especially misdiagnosed as asthma or chronic obstructive ...
Bao Le-Khac, Khoa Nguyen-Dang, Nam Vu-Hoai, Nam Nguyen-Thanh, Ngoc Duong-Minh, Thai-Hoa Tran-Ngoc, Lam Nguyen-Ho   +6 more
doaj   +1 more source

Ventilation challenge in rigid bronchoscopy: Laser tube as an alternative management in patients with lung cancer and central airway obstruction

Thoracic Cancer, 2023
Introduction Central airway tumors involving the trachea and main‐stem bronchi are a common cause of airway obstruction and a significant cause of mortality among the patients of thoracic diseases with respiratory failure. Debulking in rigid bronchoscopy
Gaetana Messina, Mary Bove, Giovanni Natale, Vincenzo Di Filippo, Giorgia Opromolla, Eva Massimilla, Mauro Forte, Anna Rainone, Giuseppe Vicario, Beatrice Leonardi, Alfonso Fiorelli, Giovanni Vicidomini, Mario Santini, Mario Pirozzi, Marianna Caterino, Carminia Maria Della Corte, Fortunato Ciardiello, Morena Fasano   +17 more
doaj   +1 more source

Does age of onset of asthma influence the effect of cigarette smoking on lung function? [PDF]

, 2016
No abstract ...
Thomson, Neil C.
core   +1 more source

The Emerging 4D Printing of Shape‐Memory Thermomorphs for Self‐Adaptative Biomedical Implants

Advanced Functional Materials, EarlyView.
4D printing enables the creation of smart implants that adapt to changing conditions in the human body over time. At the core of this technology are shape‐memory thermomorphs (SMTMs). This review offers an in‐depth analysis of 4D printing with SMTMs, emphasizing the latest advancements in smart materials, stimuli, programming principles, and their ...
Aixiang Ding, Fang Tang, Eben Alsberg
wiley   +1 more source

Lung function in Lolland‐Falster Health Study (LOFUS)

The Clinical Respiratory Journal, 2022
Background COPD prevalence in Denmark is estimated at 18% based on data from urban populations. However, studies suggest that using the clinical cut‐off for airway obstruction in population studies may overestimate prevalence.
Katja Kemp Jacobsen, Randi Jepsen, Uffe Bodtger, Knud Rasmussen, Gry St‐Martin   +4 more
doaj   +1 more source

Obstructive Sleep Apnoea: a dental perspective [PDF]

, 2003
Obstructive sleep apnoea (OSA) is regarded as a potentially life threatening breathing disorder characterised by periodic cessation of air intake during sleep.
Mulligan, Kevin M.
core  

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Predictors of tonsillectomy after previous adenoidectomy for upper airway obstruction [abstract] [PDF]

, 2010
One of the main indications for adenotonsillectomy in children is upper airway obstruction, including obstructive sleep apnea. Previous research has suggested an increased risk for requiring subsequent tonsillectomy when adenoidectomy alone is performed ...
Basler, Keith J., Mills, Jonathan C.
core  

Monitoring asthma in childhood : Lung function, bronchial responsiveness and inflammation [PDF]

, 2015
Peer reviewedPublisher ...
ERS Task Force Monitoring Asthma in Children
core   +1 more source