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Emerging Concepts in Cytokine Regulation of Airway Remodeling in Asthma. [PDF]
Immunol RevLatayan J, Akkenapally SV, Madala SK.
europepmc +1 more source
Erratum: Quantitative CT Analysis of Small Airway Remodeling in Patients with Chronic Obstructive Pulmonary Disease by a New Image Post-Processing System [Corrigendum]. [PDF]
Int J Chron Obstruct Pulmon Diseuropepmc +1 more source
Immune induction of airway remodeling
Seminars in Immunology, 2019 Airway remodeling is accepted to be a determining component within the natural history of asthma. It is a phenomenon characterized by changes in the airways structures that marches in parallel with and can be influenced by airway inflammation, floating at the interface between both natural and adaptive immunity and physical and mechanical cells ...
Guida G., Riccio A. M.
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Biologics and airway remodeling in severe asthma
Allergy: European Journal of Allergy and Clinical Immunology, 2022 Asthma is a chronic inflammatory airway disease resulting in airflow obstruction, which in part can become irreversible to conventional therapies, defining the concept of airway remodeling.
Giuseppe Spadaro +2 more
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Chest, 2003
Chronic inflammation and remodeling may follow acute inflammation or may begin insidiously as a low-grade smoldering response, especially in the case of immune reactions. The histologic hallmarks of chronic inflammation and remodeling are as follows: (1) infiltration by macrophages and lymphocytes; (2) proliferation of fibroblasts that may take the ...
Antonio M, Vignola +6 more
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Chronic inflammation and remodeling may follow acute inflammation or may begin insidiously as a low-grade smoldering response, especially in the case of immune reactions. The histologic hallmarks of chronic inflammation and remodeling are as follows: (1) infiltration by macrophages and lymphocytes; (2) proliferation of fibroblasts that may take the ...
Antonio M, Vignola +6 more
openaire +4 more sources
Current Opinion in Pharmacology, 2010
Asthmatic airway remodeling is the pathophysiological modifications of the normal airway wall structure which include changes in the composition and organization of its cellular and molecular constituents. These modifications are the major cause of the symptoms associated with decreased pulmonary function.
Rabih, Halwani +2 more
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Asthmatic airway remodeling is the pathophysiological modifications of the normal airway wall structure which include changes in the composition and organization of its cellular and molecular constituents. These modifications are the major cause of the symptoms associated with decreased pulmonary function.
Rabih, Halwani +2 more
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Seminars in Respiratory and Critical Care Medicine, 2002
Airway remodeling is a summary term for the pathological changes that occur in airway structure in allergic or suppurative airway diseases. Characteristic changes of airway remodeling in asthma include goblet cell hyperplasia, deposition of collagens in the basement membrane zone, increased size and number of microvessels in the submucosa, hyperplasia ...
Prescott G, Woodruff, John V, Fahy
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Airway remodeling is a summary term for the pathological changes that occur in airway structure in allergic or suppurative airway diseases. Characteristic changes of airway remodeling in asthma include goblet cell hyperplasia, deposition of collagens in the basement membrane zone, increased size and number of microvessels in the submucosa, hyperplasia ...
Prescott G, Woodruff, John V, Fahy
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Mechanisms of Airway Remodeling
Chest, 2013Airway remodeling comprises the structural changes of airway walls, induced by repeated injury and repair processes. It is characterized by the changes of tissue, cellular, and molecular composition, affecting airway smooth muscle, epithelium, blood vessels, and extracellular matrix.
Nobuaki, Hirota, James G, Martin
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Airway remodeling in the pathogenesis of asthma
Current Allergy and Asthma Reports, 2001The inflammatory and remodelling processes that underlie asthma result from a highly complex interaction between various cell types. Apart from inflammatory cells, such as eosinophils, activated T cells, mast cells and macrophages, structural tissue cells such as epithelial cells, fibroblasts and smooth muscle cells can also play an important effector ...
Vignola AM +6 more
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International Immunopharmacology, 2011 Asthma is a chronic airway disease characterized by increased airway hyperresponsiveness, airway inflammation, and airway remodeling including collagen deposition in subepithelial regions.
Anurag Agrawal +2 more
exaly +2 more sources