Results 231 to 240 of about 45,718 (290)

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Oxymatrine Inhibits Epithelial-Mesenchymal Transition to Alleviate Airway Remodeling in Chronic Obstructive Pulmonary Disease by Suppressing the TGF-β1/Smad Pathway. [PDF]

Kaohsiung J Med Sci
Zhou S, Zhu JX, Li J.
europepmc   +1 more source

Evaluation of Small Airways Dysfunction With Dupilumab Using Airway Oscillometry in Uncontrolled Severe Asthma

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 264-266, March 2025.
Kirsten E. Stewart, Chris RuiWen Kuo, Rory Chan, Brian J. Lipworth   +3 more
wiley   +1 more source

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

The FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar, Céline Philippe, Eric Chevet, Jiří Zahradník   +3 more
wiley   +1 more source

PiSlope: A New Tool to Evaluate Airway Remodeling. [PDF]

Radiology
Lynch DA.
europepmc   +1 more source

Respiratory Viral Infections and the Tonsillar Transcriptome: An Exploratory Study

Clinical &Experimental Allergy, EarlyView.
Tanzeela Hanif, Lotta E. Ivaska, Antti Silvoniemi, Emilia Mikola, Tuomo Puhakka, Oscar Palomares, Sanna Toppila‐Salmi, Mubeccel Akdis, Cezmi A. Akdis, Tuomas Jartti   +9 more
wiley   +1 more source

The 2025 ATS/ERS update of the international multidisciplinary classification of the interstitial pneumonias: implications for the pathologist

Histopathology, EarlyView.
This review highlights changes relevant to pathologists in the updated multidisciplinary classification of interstitial pneumonias. Changes include expansion beyond idiopathic disease, subclassification as interstitial (fibrotic vs non‐fibrotic) and alveolar filling disorders, expansion to include additional patterns (e.g.
Andrew G Nicholson, Wendy A. Cooper, Aurelie Fabre, William Travis, Lida P. Hariri, Ayodeji Adegunsoye, Sara Piciucchi, Christopher J Ryerson   +7 more
wiley   +1 more source

Retraction: Effects of microRNA-19b on airway remodeling, airway inflammation and degree of oxidative stress by targeting TSLP through the Stat3 signaling pathway in a mouse model of asthma. [PDF]

Oncotarget
Ye L, Mou Y, Wang J, Jin ML.
europepmc   +1 more source

Population‐Scale Plasma Proteomics Reveals Systemic Inflammatory Signatures Associated With Chronic Rhinosinusitis

Clinical &Experimental Allergy, EarlyView.
Dachan Kim, Hyung‐Ju Cho, Chang‐Hoon Kim, Min‐Seok Rha   +3 more
wiley   +1 more source

Circular RNA FCHO2 promotes airway remodeling in COPD via regulating nuclear translocation of PTBP1 to repress the splicing of GRN pre-mRNA. [PDF]

Cell Death Dis
Liu Y, Wang Y, Fei Y, Xu H, Xue C, Li L, Huang L, Liu P, Li R, Shan G, Chen L, Zhao D.   +11 more
europepmc   +1 more source