Results 111 to 120 of about 1,534,638 (251)

Altered actin isoforms expression and enhanced airway responsiveness in asthma: the crucial role of β-cytoplasmic actin

Frontiers in Physiology
Airway hyperresponsiveness, caused by excessive contraction of airway smooth muscle, is a characteristic of asthma involving multiple proteins, including various isoforms of actin and myosin.
Marisol Alvarez-González, Angélica Flores-Flores, Angélica Flores-Flores, Verónica Carbajal-Salinas, Blanca Bazán-Perkins, Blanca Bazán-Perkins   +5 more
doaj   +1 more source

Intelligent Continuum Micromachines in Complex Confined Spaces

SmartBot, EarlyView.
The cover depicts a conceptual design for an intelligent continuum micromachine entering a target capsule used in fusion‐energy research through its slender gas‐fill tube. By combining route‐adaptive deformation, embedded sensing, and a functional end effector, the robot could inspect hidden defects, assess local conditions, and support localized ...
Huayang Sai, Yunyue Yang, Shuxing Xu, Jinbo Hu, Jiliang Wang, Zhehao Gan, Wei Tang, Tian‐Yun Huang   +7 more
wiley   +1 more source

Bronchial thermoplasty and the role of airway smooth muscle: are we on the right direction?

, 2017
Francesco Menzella,1 Mirco Lusuardi,2 Carla Galeone,1 Nicola Facciolongo1 1Department of Medical Specialties, Pneumology Unit, IRCCS – Arcispedale Santa Maria Nuova, Reggio Emilia, 2Unit of Respiratory Rehabilitation, AUSL Reggio Emilia, S  ...
Galeone C, Menzella F, Facciolongo N, Lusuardi M   +3 more
core  

Sargassum Lung Syndrome: Air Flow Obstruction and Bronchial Inflammation Are Observed After Prolonged Exposure to Sargassum Gas Emissions in the Eastern Caribbean

Environmental Toxicology, EarlyView.
ABSTRACT Sargassum inundation of Caribbean and American shorelines is a growing environmental hazard. Hydrogen sulfide (H2S) and ammonia (NH3) produced by decomposing Sargassum could be involved in airway obstruction and bronchial inflammation. The study was undertaken to evaluate the effects of exposure to H2S and NH3 gases emitted during Sargassum ...
Rishika Banydeen, Jonathan Florentin, Maxime Boutourlinsky, Remi Nguyen, Fatima Radouani, Moustapha Agossou, Gary Lutin, Thierry Lebrun, Remi Neviere, Dabor Resiere   +9 more
wiley   +1 more source

Transoral Robotic Resection of Glossopharyngeal Neurofibroma: A Case Report

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This case highlights the diagnostic challenges posed by rare oropharyngeal neurofibromas, their potential to mimic other conditions, and the novel application of transoral robotic surgery (TORS) for the management of an oropharyngeal neurofibroma. A 47‐year‐old female presented with a 1‐year history of a left tonsillar mass.
Cody L. Messick, Austin R. Swisher, Hannah M. Gibbs, Michael T. Sramek, Laura Klusovsky, Payam Entezami, James S. Lewis Jr., Brent A. Chang   +7 more
wiley   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source

Hemodynamic Effects of Prolonged Apneic Oxygenation in Laryngologic Surgery: A Randomized Controlled Pilot Trial

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Limited data exist on cardiocirculatory responses associated with extended periods of apnea during administration of high‐flow nasal oxygen for laryngologic surgery (apneic oxygenation with HFNO, AO‐HFNO). The possibility of hemodynamic compromise in the settings of acute hypercapnia, respiratory acidosis, hyperoxia, and IV ...
Vladimir Nekhendzy, Hendrikus J. Lemmens, Amit R. Saxena, Brita M. Mittal, Edward J. Damrose, C. Kwang Sung, Raffick Bowen   +6 more
wiley   +1 more source

The effects of omalizumab on IgE-induced cytokine synthesis by asthmatic airway smooth muscle cells

, 2010
Human airway smooth muscle cells (ASMCs) express high- and low-affinity IgE receptors and respond to IgE, thereby contributing to airway ...
Tamm, Michael, Roth, Michael, Roth M, Tamm M, Michael Roth, Michael Tamm   +5 more
core   +1 more source

Cardiovascular Plasticity and Adaptation of High‐Altitude Birds and Mammals

Integrative Zoology, EarlyView.
This schematic depicts the cardiovascular adaptations of mammals and birds to high‐altitude hypoxia. It highlights key phenotypic changes in oxygen transport and cardiac responses, driven by molecular mechanisms including transcriptional regulation and genetic modifications.
Huishang She, Yanhua Qu
wiley   +1 more source

Targeting NLRP3 with GDC-2394 ameliorates airway inflammation and smooth muscle hyperplasia in experimental asthma by suppressing the IL-6/JAK2/STAT3 axis

Scientific Reports
Uncontrolled childhood asthma contributes to chronic airway inflammation and remodeling, primarily characterized by bronchial smooth muscle hyperplasia. Although the NLR family pyrin domain-containing 3 (NLRP3) inflammasome regulates airway inflammation,
Zhiyuan Wang, Zhenzhen Guo, Yanan Wang, Qianqian Dai, Muhammad Imran Arif, Aizetiguli Maiming, Menghua Li, Aliya Maimaitiniyazi, Xueli Wang, Jianjiang Cui, Shengmeng Qu, Wen Zhao, Liang Ru   +12 more
doaj   +1 more source