Results 141 to 150 of about 1,534,638 (251)

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Oxidized phosphatidylcholines inhibit airway smooth muscle β2-adrenergic receptors via protein kinase C. [PDF]

Am J Respir Cell Mol Biol
Vaghasiya J, Sikarwar A, Dalvand A, Basu S, Bagan A, Varghese N, Duaqui AA, Pandey D, Mishra S, Ravandi A, Pascoe CD, Halayko AJ, Canadian Respiratory Research Network.   +12 more
europepmc   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

Immunology &Cell Biology, EarlyView.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

Hypercapnia enhances airway smooth muscle contractility via STIM1-dependent Ca2+ signaling. [PDF]

JCI Insight
Shigemura M, Kryvenko V, Pacheco JA, Puckelwartz MJ, Aleksic M, Magnani ND, Thompson E, Martin-Romero FJ, Cummins EP, Seeger W, Bräuninger A, Welch LC, Budinger GRS, Lecuona E, Dada LA, Bharat A, Vadász I, Prakriya M, Sznajder JI.   +18 more
europepmc   +1 more source

Syrinx anatomy and vocalizations in New World vultures (Aves: Cathartidae): Implications for avian vocal evolution

Journal of Anatomy, EarlyView.
New World vultures are the only avian clade proposed to lack a syrinx and have been described as non‐vocal. Using dissection, diceCT, and histology, we demonstrate that cathartid vultures have novel syringeal features that form a syrinx and vocal characterization reveals that they produce more complex vocalizations than previously reported.
Bradley A. Ibarra, Carmen A. Urban, Lucas J. Legendre, Julia A. Clarke   +3 more
wiley   +1 more source

Interleukin-13 R130Q aggravates airway smooth-muscle phenotypic switching and promotes airway remodeling in severe asthma. [PDF]

Front Physiol
He Y, Sun J, Li L, Bai S, Zhai X, Tian Y, Pan Q, Bao Y, Ding G.   +8 more
europepmc   +1 more source

The XenCart Protocol: A method for Alcian blue labeling and quantitative analysis of craniofacial cartilage in Xenopus

Journal of Anatomy, EarlyView.
The XenCart Protocol provides a reproducible way to visualize and quantify how the developing craniofacial skeleton responds to experimental perturbation. Embryos are exposed to defined conditions, craniofacial cartilage is stained with Alcian blue, imaged, and analyzed morphometrically.
Umar Aziz, Leona Bhandari, Claudia Lizama, Riya Maurya, Amanda J. G. Dickinson   +4 more
wiley   +1 more source

ROS scavenging mitigates TNFα-induced endoplasmic reticulum stress and mitochondrial fragmentation in human airway smooth muscle. [PDF]

Function (Oxf)
Dasgupta D, Mahadev Bhat S, Sieck GC.
europepmc   +1 more source

Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley   +1 more source

Differences in Tongue Muscle Activity During Chewing of Rice With Various Textures

Journal of Oral Rehabilitation, EarlyView.
During chewing, tongue muscle activity increased in the late stage for softer, wetter and more cohesive boluses, showing a pattern distinct from the masseter and suprahyoid muscles. These findings suggest that tongue muscle activity is modulated according to bolus properties and may contribute to bolus gathering, shaping and transport.
Chisato Aizawa, Jin Magara, Anna Sasa, Reiko Ita, Takanori Tsujimura, Makoto Inoue   +5 more
wiley   +1 more source