Akirin colocalizes with subunits of the SWI/SNF-class Brahma chromatin remodeling complex.
, 2012 (A–C) Detail of polytene chromosome squashes demonstrating immunocolocalization of Akirin with Brm complex subunits. See Figure S9 for whole genome squash images.
Hitoshi Aihara (180458) +4 more
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Molecular Biology of the Cell, 2013 During meiosis, evolutionarily conserved mechanisms regulate chromosome remodeling, leading to the formation of a tight bivalent structure. This bivalent, a linked pair of homologous chromosomes, is essential for proper chromosome segregation in meiosis.
Clemons, Amy M. +7 more
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The change in Akirin relative expression assessed 3-days post-RNAi treatment.
, 2020 The relative expression of Akirin was significantly downregulated by a mean factor of 0.76 (p = 0.02), when comparing the expression ratios between the Akirin dsRNA treated samples and the negative control samples.
Yael Dahan-Moss (4578901) +2 more
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Estudos do efeito da proteína recombinante Akirin na infeção por Plasmodium berghei em Anopheles gambiae s.s. [PDF]
, 2012 A malária é considerada uma das doenças mais importantes transmitida pelos mosquitos, tendo um grande impacto nos países não desenvolvidos. O controlo da malária continua fortemente dependente do uso de fármacos e estratégias para controlo do vetor. Como
COSTA, Mário João Amaro da
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Akirin and the BRM complex co-occupy the Dmef2 enhancer during embryogenesis.
, 2012 Chromatin immunoprecipitations were performed on extracts prepared from 2–4, 4–6, and 6–10 hour-old yw (Blue bars) and akirin2 mutant (Red bars) embryos using anti-Twist (A), anti-Akirin (B), and anti-Moira (C) antibodies.
Hitoshi Aihara (180458) +4 more
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Interactions Between akirin and simjoang During Cardiac Development
One of the most fundamental organs to form during the earliest stages of development is the heart. In the fruit fly (Drosophila melanogaster), many genes and proteins work together for the formation of a fully functioning heart.
Hadjimirzaei, Armeta, Nowak, Scott J
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From Proteins to Muscles: looking at the Interaction Between the Protein Akirin and Simjoang
, 2023 One of the most fundamental organs to form during the earliest stages of development is the heart. In the fruit fly (Drosophila melanogaster), many genes and proteins work together for the formation of a fully functioning heart.
Hadjimirzaei, Armeta, Nowak, Scott J
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Mosquito gene targeted RNAi studies for vector control. [PDF]
Funct Integr Genomics, 2023 Yadav M, Dahiya N, Sehrawat N.
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The Potential Biological Roles of Circular RNAs in the Immune Systems of Insects to Pathogen Invasion. [PDF]
Genes (Basel), 2023 Abbas MN +6 more
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Evolutionary plasticity in the innate immune function of Akirin
, 2017 Eukaryotic gene expression requires the coordinated action of transcription factors, chromatin remodelling complexes and RNA polymerase. The conserved nuclear protein Akirin plays a central role in immune gene expression in insects and mammals, linking ...
Olivier Zugasti +9 more
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